Sub-toxic cisplatin concentrations induce extensive chromosomal, nuclear and nucleolar abnormalities associated with high malignancy before acquired resistance develops: Implications for clinical caution

• John G. Delinassios ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft

  * E-mail: jg.delinassios@gmail.com (JGD); all@anticancer.com (RMH)

  Affiliation International Institute of Anticancer Research, Kapandriti, Attica, Greece

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• Robert M. Hoffman ,

  Roles Visualization, Writing – review & editing

  * E-mail: jg.delinassios@gmail.com (JGD); all@anticancer.com (RMH)

  Affiliations Department of Surgery, University of California, La Jolla, California, United States of America, AntiCancer Inc., San Diego, San Diego, California, United States of America

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• George Koumakis,

  Roles Data curation, Investigation, Methodology

  Current address: Basel, Switzerland

  Affiliation International Institute of Anticancer Research, Kapandriti, Attica, Greece

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• Dimitrios Palitskaris,

  Roles Software, Visualization, Writing – review & editing

  Affiliation International Institute of Anticancer Research, Kapandriti, Attica, Greece

  https://orcid.org/0009-0000-2799-1842

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• Kyriaki-Nefelli Poulatsidou,

  Roles Data curation, Formal analysis, Validation

  Affiliation International Institute of Anticancer Research, Kapandriti, Attica, Greece

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• George J. Delinasios

  Roles Methodology, Supervision, Writing – review & editing

  Affiliation International Institute of Anticancer Research, Kapandriti, Attica, Greece

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