Luteolin target HSPB1 regulates endothelial cell ferroptosis to protect against radiation vascular injury

Li Wen; Weiyuan Zhang; Jia Hu; Tao Chen; Yiming Wang; Changchang Lv; Min Li; Lisheng Wang; Fengjun Xiao

doi:10.1371/journal.pone.0311922

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Open Access

Peer-reviewed

Research Article

Luteolin target HSPB1 regulates endothelial cell ferroptosis to protect against radiation vascular injury

Li Wen,

Roles Formal analysis, Methodology, Writing – original draft

Affiliation School of Nursing, Jilin University, Changchun, P. R. China
⨯
Weiyuan Zhang,

Roles Data curation, Software

Affiliations Department of Special Medicine, School of Basic Medicine, Qingdao University, Qingdao, P. R. China, Laboratory of Molecular Diagnosis and Regenerative Medicine, The Affiliated Hospital of Qingdao University, Qingdao, P. R. China
⨯
Jia Hu,

Roles Validation, Writing – original draft

Affiliation Department of Cardiovascular, The Sixth Medical Center of Chinese PLA General Hospital, Haidian District, Beijing, China
⨯
Tao Chen,

Roles Validation

Affiliation Department of Cardiovascular, The Sixth Medical Center of Chinese PLA General Hospital, Haidian District, Beijing, China
⨯
Yiming Wang,

Roles Data curation, Writing – original draft

Affiliation School of Nursing, Jilin University, Changchun, P. R. China
⨯
Changchang Lv,

Roles Formal analysis, Writing – original draft

Affiliation School of Nursing, Jilin University, Changchun, P. R. China
⨯
Min Li ,

Roles Resources, Supervision, Writing – review & editing

* E-mail: limin82057@163.com (ML); lishengwang@jlu.edu.cn (LW); xiaofjun1105@163.com (FX)

Affiliation Beijing Institute of Radiation Medicine, Beijing, P. R. China
⨯
Lisheng Wang ,

Roles Conceptualization, Project administration, Visualization, Writing – review & editing

* E-mail: limin82057@163.com (ML); lishengwang@jlu.edu.cn (LW); xiaofjun1105@163.com (FX)

Affiliations School of Nursing, Jilin University, Changchun, P. R. China, Laboratory of Molecular Diagnosis and Regenerative Medicine, The Affiliated Hospital of Qingdao University, Qingdao, P. R. China
⨯
Fengjun Xiao

Roles Conceptualization, Funding acquisition, Writing – review & editing

* E-mail: limin82057@163.com (ML); lishengwang@jlu.edu.cn (LW); xiaofjun1105@163.com (FX)

Affiliation Beijing Institute of Radiation Medicine, Beijing, P. R. China

https://orcid.org/0009-0003-8153-8987

⨯

Luteolin target HSPB1 regulates endothelial cell ferroptosis to protect against radiation vascular injury

Li Wen,
Weiyuan Zhang,
Jia Hu,
Tao Chen,
Yiming Wang,
Changchang Lv,
Min Li,
Lisheng Wang,
Fengjun Xiao

Published: October 11, 2024
https://doi.org/10.1371/journal.pone.0311922

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