Targeting of oxidized Macrophage Migration Inhibitory Factor (oxMIF) with antibody ON104 attenuates the severity of glomerulonephritis

Maroua Ferhat; Julia Mayer; Lyndon H. Costa; Maria Prendecki; Alejandro A. Puchol Tarazona; Alexander Schinagl; Randolf J. Kerschbaumer; Frederick W. K. Tam; Christine Landlinger; Michael Thiele

doi:10.1371/journal.pone.0311837

Loading metrics

Open Access

Peer-reviewed

Research Article

Targeting of oxidized Macrophage Migration Inhibitory Factor (oxMIF) with antibody ON104 attenuates the severity of glomerulonephritis

Maroua Ferhat,

Roles Formal analysis, Methodology, Writing – original draft, Writing – review & editing

Affiliation OncoOne Research & Development GmbH, Vienna, Austria

https://orcid.org/0000-0002-1298-4620

⨯
Julia Mayer,

Roles Methodology, Writing – review & editing

Affiliation OncoOne Research & Development GmbH, Vienna, Austria
⨯
Lyndon H. Costa,

Roles Methodology, Writing – review & editing

Affiliation Department of Immunology and Inflammation, Centre for Inflammatory Disease, Hammersmith Hospital, Imperial College London (ICL), London, United Kingdom
⨯
Maria Prendecki,

Roles Methodology, Writing – review & editing

Affiliation Department of Immunology and Inflammation, Centre for Inflammatory Disease, Hammersmith Hospital, Imperial College London (ICL), London, United Kingdom
⨯
Alejandro A. Puchol Tarazona,

Roles Methodology, Writing – review & editing

Affiliation OncoOne Research & Development GmbH, Vienna, Austria
⨯
Alexander Schinagl,

Roles Funding acquisition, Validation, Writing – review & editing

Affiliation OncoOne Research & Development GmbH, Vienna, Austria

https://orcid.org/0000-0002-6060-969X

⨯
Randolf J. Kerschbaumer,

Roles Funding acquisition, Validation, Writing – review & editing

Affiliation OncoOne Research & Development GmbH, Vienna, Austria
⨯
Frederick W. K. Tam,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Department of Immunology and Inflammation, Centre for Inflammatory Disease, Hammersmith Hospital, Imperial College London (ICL), London, United Kingdom
⨯
Christine Landlinger ,

Contributed equally to this work with: Christine Landlinger, Michael Thiele

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation OncoOne Research & Development GmbH, Vienna, Austria
⨯
Michael Thiele

Contributed equally to this work with: Christine Landlinger, Michael Thiele

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: michael.thiele@oncoone.com

Affiliation OncoOne Research & Development GmbH, Vienna, Austria

https://orcid.org/0000-0002-3003-9999

⨯

Targeting of oxidized Macrophage Migration Inhibitory Factor (oxMIF) with antibody ON104 attenuates the severity of glomerulonephritis

Maroua Ferhat,
Julia Mayer,
Lyndon H. Costa,
Maria Prendecki,
Alejandro A. Puchol Tarazona,
Alexander Schinagl,
Randolf J. Kerschbaumer,
Frederick W. K. Tam,
Christine Landlinger,
Michael Thiele

Published: October 7, 2024
https://doi.org/10.1371/journal.pone.0311837

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Neutrophils
Is the Subject Area "Neutrophils" applicable to this article?

Thanks for your feedback.
Enzyme-linked immunoassays
Is the Subject Area "Enzyme-linked immunoassays" applicable to this article?

Thanks for your feedback.
Kidneys
Is the Subject Area "Kidneys" applicable to this article?

Thanks for your feedback.
Glomeruli
Is the Subject Area "Glomeruli" applicable to this article?

Thanks for your feedback.
Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Urine
Is the Subject Area "Urine" applicable to this article?

Thanks for your feedback.
Glomerulonephritis
Is the Subject Area "Glomerulonephritis" applicable to this article?

Thanks for your feedback.
Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.