Network pharmacology combined with experimental validation show that apigenin as the active ingredient of Campsis grandiflora flower against Parkinson’s disease by inhibiting the PI3K/AKT/NF-κB pathway

• Kai Liu,

  Roles Formal analysis, Visualization, Writing – original draft

  Affiliations Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Department of Neurosurgery, People’s Hospital of Rizhao, Jining Medical College, Rizhao, Shandong, China

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• Jing An,

  Roles Data curation, Software, Visualization, Writing – original draft

  Affiliation Department of Pathology, People’s Hospital of Rizhao, Jining Medical College, Rizhao, Shandong, China

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• Jing Zhang,

  Roles Data curation, Software, Writing – original draft

  Affiliation Department of Pharmacy, Jining Medical College, Rizhao, Shandong, China

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• Jihu Zhao,

  Roles Formal analysis, Visualization, Writing – original draft

  Affiliation Department of Neurosurgery, The Affiliated Hospital of Qingdao University, Qingdao, China

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• Peng Sun,

  Roles Conceptualization, Methodology, Project administration, Writing – review & editing

  Affiliation Department of Neurosurgery, The Affiliated Hospital of Qingdao University, Qingdao, China

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• Zhaohui He

  Roles Conceptualization, Methodology, Project administration, Writing – review & editing

  * E-mail: geno_he@163.com

  Affiliation Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

  https://orcid.org/0009-0009-3835-6639

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