Aging-induced dysbiosis worsens sepsis severity but is attenuated by probiotics in D-galactose-administered mice with cecal ligation and puncture model

• Chalisa Pinitchun ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft

  * E-mail: chalisap16@hotmail.com (CP); aleelahavanit@gmail.com (AL)

  Affiliations Department of Microbiology, Center of Excellence on Translational Research in Inflammation and Immunology (CETRII), Chulalongkorn University, Bangkok, Thailand, Faculty of Medicine, Department of Microbiology, Chulalongkorn University, Bangkok, Thailand, Faculty of Allied Health Sciences, Department of Transfusion Sciences and Clinical Microbiology, Chulalongkorn University, Bangkok, Thailand

  https://orcid.org/0009-0005-7299-3640

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• Wimonrat Panpetch,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Faculty of Science, Department of Microbiology, Burapha University, Chonburi, Thailand

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• Thansita Bhunyakarnjanarat,

  Roles Formal analysis, Methodology

  Affiliations Department of Microbiology, Center of Excellence on Translational Research in Inflammation and Immunology (CETRII), Chulalongkorn University, Bangkok, Thailand, Faculty of Medicine, Department of Microbiology, Chulalongkorn University, Bangkok, Thailand

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• Kanyarat Udompornpitak,

  Roles Formal analysis, Methodology

  Affiliations Department of Microbiology, Center of Excellence on Translational Research in Inflammation and Immunology (CETRII), Chulalongkorn University, Bangkok, Thailand, Faculty of Medicine, Department of Microbiology, Chulalongkorn University, Bangkok, Thailand

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• Huy Thanh Do,

  Roles Methodology

  Affiliation Department of Microbiology, Center of Excellence on Translational Research in Inflammation and Immunology (CETRII), Chulalongkorn University, Bangkok, Thailand

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• Peerapat Visitchanakun,

  Roles Methodology

  Affiliations Department of Microbiology, Center of Excellence on Translational Research in Inflammation and Immunology (CETRII), Chulalongkorn University, Bangkok, Thailand, Faculty of Medicine, Department of Microbiology, Chulalongkorn University, Bangkok, Thailand

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• Dhammika Leshan Wannigama,

  Roles Resources

  Affiliations Faculty of Medicine, Department of Microbiology, Chulalongkorn University, Bangkok, Thailand, Department of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan, Department of Infectious Diseases and Infection Control, Pathogen Hunter’s Research Collaborative Team, Yamagata Prefectural Central Hospital, Yamagata, Japan, Yamagata Prefectural University of Health Sciences, Yamagata, Japan, Faculty of Health and Medical Sciences, School of Medicine, The University of Western Australia, Perth, WA, Australia, Biofilms and Antimicrobial Resistance Consortium of ODA Receiving Countries, The University of Sheffield, Sheffield, United Kingdom

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• Suwasin Udomkarnjananun,

  Roles Formal analysis

  Affiliation Faculty of Medicine, Department of Medicine, Division of Nephrology, Chulalongkorn University, Bangkok, Thailand

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• Monruedee Sukprasansap,

  Roles Resources

  Affiliation Institute of Nutrition, Food Toxicology Unit, Mahidol University, Salaya Campus, Phutthamonthon, Na-khonpathom, Salaya, Thailand

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• Tewin Tencomnao,

  Roles Resources

  Affiliations Faculty of Allied Health Sciences, Center of Excellence on Natural Products for Neuroprotection and Anti-Ageing (Neur-Age Natura), Chulalongkorn University, Bangkok, Thailand, Faculty of Allied Health Sciences, Department of Clinical Chemistry, Chulalongkorn University, Bangkok, Thailand

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• Pattarin Tangtanatakul,

  Roles Investigation, Project administration, Writing – review & editing

  Affiliations Department of Microbiology, Center of Excellence on Translational Research in Inflammation and Immunology (CETRII), Chulalongkorn University, Bangkok, Thailand, Faculty of Medicine, Department of Microbiology, Chulalongkorn University, Bangkok, Thailand, Faculty of Allied Health Sciences, Department of Transfusion Sciences and Clinical Microbiology, Chulalongkorn University, Bangkok, Thailand

  https://orcid.org/0000-0001-8978-6916

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• Asada Leelahavanichkul

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: chalisap16@hotmail.com (CP); aleelahavanit@gmail.com (AL)

  Affiliations Department of Microbiology, Center of Excellence on Translational Research in Inflammation and Immunology (CETRII), Chulalongkorn University, Bangkok, Thailand, Faculty of Medicine, Department of Microbiology, Chulalongkorn University, Bangkok, Thailand, Faculty of Science, Department of Microbiology, Burapha University, Chonburi, Thailand

  https://orcid.org/0000-0002-5566-6403

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