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Open Access
Peer-reviewed
Research Article
Shift from visceral to subcutaneous adipose tissue in Cyp17a1-knockout rats prevents the progression of metabolic syndrome
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Beom-Jin Jeon ,
Contributed equally to this work with: Beom-Jin Jeon, Jeong-Hwa Lee
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft
Affiliations Laboratory of Theriogenology and Biotechnology, Department of Veterinary Clinical Science, College of Veterinary Medicine, BK21 FOUR Future Veterinary Medicine Leading Education, and the Research Institute of Veterinary Science, Seoul National University, Seoul, Republic of Korea, Comparative medicine Disease Research Center, Seoul National University, Seoul, Republic of Korea
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Jeong-Hwa Lee ,
Contributed equally to this work with: Beom-Jin Jeon, Jeong-Hwa Lee
Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing
Affiliations K-BIO KIURI Center, Seoul National University, Seoul, Republic of Korea, Department of Veterinary Nutrition, College of Veterinary Medicine, Seoul National University, Republic of Korea
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Dong-Hyeok Kwon,
Roles Methodology
Affiliations Laboratory of Theriogenology and Biotechnology, Department of Veterinary Clinical Science, College of Veterinary Medicine, BK21 FOUR Future Veterinary Medicine Leading Education, and the Research Institute of Veterinary Science, Seoul National University, Seoul, Republic of Korea, Comparative medicine Disease Research Center, Seoul National University, Seoul, Republic of Korea
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Hee-Kyoung Kim,
Roles Investigation, Methodology
Affiliations Laboratory of Theriogenology and Biotechnology, Department of Veterinary Clinical Science, College of Veterinary Medicine, BK21 FOUR Future Veterinary Medicine Leading Education, and the Research Institute of Veterinary Science, Seoul National University, Seoul, Republic of Korea, Comparative medicine Disease Research Center, Seoul National University, Seoul, Republic of Korea
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Goo Jang
Roles Conceptualization, Project administration, Supervision, Writing – review & editing
* E-mail: snujang@snu.ac.kr
Affiliations Laboratory of Theriogenology and Biotechnology, Department of Veterinary Clinical Science, College of Veterinary Medicine, BK21 FOUR Future Veterinary Medicine Leading Education, and the Research Institute of Veterinary Science, Seoul National University, Seoul, Republic of Korea, Comparative medicine Disease Research Center, Seoul National University, Seoul, Republic of Korea, LARTBio Incorp., Gyeonggi-Do, Republic of Korea
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Shift from visceral to subcutaneous adipose tissue in Cyp17a1-knockout rats prevents the progression of metabolic syndrome
- Beom-Jin Jeon,
- Jeong-Hwa Lee,
- Dong-Hyeok Kwon,
- Hee-Kyoung Kim,
- Goo Jang
- Published: December 12, 2025
- https://doi.org/10.1371/journal.pone.0311478