Alpha-fetoprotein and des-gamma-carboxy prothrombin can predict the objective response of patients with hepatocellular carcinoma receiving durvalumab plus tremelimumab therapy

• Issei Saeki ,

  Roles Conceptualization, Data curation, Formal analysis, Writing – original draft

  * E-mail: issaeki@yamaguchi-u.ac.jp

  Affiliation Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan

  https://orcid.org/0000-0001-5885-5042

  ⨯
• Shigeo Shimose,

  Roles Conceptualization, Data curation

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan

  ⨯
• Tetsu Tomonari,

  Roles Data curation

  Affiliation Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School of Medicine, Tokushima, Japan

  ⨯
• Takanori Ito,

  Roles Data curation

  Affiliation Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan

  ⨯
• Joji Tani,

  Roles Data curation

  Affiliation Department of Gastroenterology and Neurology, Kagawa University, Faculty of Medicine, Kagawa, Japan

  ⨯
• Yasuto Takeuchi,

  Roles Data curation

  Affiliation Department of Regenerative Medicine, Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan

  ⨯
• Naoki Yoshioka,

  Roles Data curation

  Affiliation Department of Gastroenterology and Hepatology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Aichi, Japan

  ⨯
• Takehito Naito,

  Roles Data curation

  Affiliation Department of Gastroenterology, Toyohashi Municipal Hospital, Toyohashi, Aichi, Japan

  ⨯
• Mamiko Takeuchi,

  Roles Data curation

  Affiliation Department of Gastroenterology, Anjo Kosei Hospital, Anjo, Japan

  ⨯
• Satoru Kakizaki,

  Roles Data curation

  Affiliation Department of Clinical Research, NHO Takasaki General Medical Center, Takasaki, Gunma, Japan

  https://orcid.org/0000-0003-0224-7093

  ⨯
• Takeshi Hatanaka,

  Roles Data curation

  Affiliation Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Maebashi, Japan

  ⨯
• Kyo Sasaki,

  Roles Data curation

  Affiliation Department of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Japan

  ⨯
• Tetsuya Yasunaka,

  Roles Data curation

  Affiliation Department of Gastroenterology, Fukuyama City Hospital, Okayama, Japan

  ⨯
• Masahiro Sakata,

  Roles Data curation

  Affiliation Department of Gastroenterology, NHO Fukuyama Medical Center, Fukuyama, Japan

  ⨯
• Hideki Iwamoto,

  Roles Data curation

  Affiliations Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan, Iwamoto Internal Medical Clinic, Kitakyusyu, Japan

  ⨯
• Satoshi Itano,

  Roles Data curation

  Affiliation Department of Gastroenterology and Hepatology, Kurume Central Hospital, Kurume, Japan

  ⨯
• Tomotake Shirono,

  Roles Data curation

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan

  ⨯
• Norikazu Tanabe,

  Roles Data curation

  Affiliations Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan, Division of Laboratory, Yamaguchi University Hospital, Yamaguchi, Japan

  ⨯
• Takafumi Yamamoto,

  Roles Data curation

  Affiliation Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan

  ⨯
• Yuki Kanayama,

  Roles Data curation

  Affiliation Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Maebashi, Japan

  ⨯
• Atsushi Naganuma,

  Roles Data curation

  Affiliation Department of Gastroenterology, NHO Takasaki General Medical Center, Takasaki, Gunma, Japan

  ⨯
• Sohji Nishina,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Japan

  ⨯
• Motoyuki Otsuka,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Okayama University Hospital, Okayama, Japan

  https://orcid.org/0000-0003-2869-2881

  ⨯
• Hideki Kobara,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Neurology, Kagawa University, Faculty of Medicine, Kagawa, Japan

  https://orcid.org/0000-0002-8508-827X

  ⨯
• Hiroki Kawashima,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan

  ⨯
• Tetsuji Takayama,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School of Medicine, Tokushima, Japan

  ⨯
• Takumi Kawaguchi,

  Roles Writing – review & editing

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan

  ⨯
• Takahiro Yamasaki,

  Roles Writing – review & editing

  Affiliation Department of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan

  https://orcid.org/0000-0002-9793-0399

  ⨯
• Taro Takami,

  Roles Writing – review & editing

  Affiliation Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan

  https://orcid.org/0000-0002-6689-4989

  ⨯
•  [ ... ],
• Hepatology InVestigator Experts in Japan (HIVE-J) Study Group

  ¶Membership of the Hepatology InVestigator Experts in Japan (HIVE-J) Study Group is listed in the Acknowledgments.

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