Apolipoprotein A-I priming via SR-BI and ABCA1 receptor binding upregulates mitochondrial metabolism to promote insulin secretion in INS-1E cells

• Claire L. Lyons ,

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  ¶‡ CLL and EC are joint first authors. LE and JOL are joint senior authors.

  Affiliation Department of Experimental Medical Sciences, Unit of Medical Protein Science, Lund University, Lund, Sweden

  ⨯
• Elaine Cowan ,

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  * E-mail: jens.lagerstedt@med.lu.se (JOL); lena.eliasson@med.lu.se (LE); elaine.cowan@med.lu.se (EC)

  ¶‡ CLL and EC are joint first authors. LE and JOL are joint senior authors.

  Affiliation Department of Clinical Sciences, Unit of Islet Cell Exocytosis, Lund University Diabetes Centre, Malmö, Sweden

  ⨯
• Oktawia Nilsson,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Experimental Medical Sciences, Unit of Medical Protein Science, Lund University, Lund, Sweden

  ⨯
• Manca Mohar,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Experimental Medical Sciences, Unit of Medical Protein Science, Lund University, Lund, Sweden

  ⨯
• Pablo Peña-Martínez,

  Roles Investigation, Writing – review & editing

  Affiliation Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden

  ⨯
• Lena Eliasson ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Writing – original draft

  * E-mail: jens.lagerstedt@med.lu.se (JOL); lena.eliasson@med.lu.se (LE); elaine.cowan@med.lu.se (EC)

  ¶‡ CLL and EC are joint first authors. LE and JOL are joint senior authors.

  Affiliation Department of Clinical Sciences, Unit of Islet Cell Exocytosis, Lund University Diabetes Centre, Malmö, Sweden

  ⨯
• Jens O. Lagerstedt

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft

  * E-mail: jens.lagerstedt@med.lu.se (JOL); lena.eliasson@med.lu.se (LE); elaine.cowan@med.lu.se (EC)

  ¶‡ CLL and EC are joint first authors. LE and JOL are joint senior authors.

  Affiliations Department of Experimental Medical Sciences, Unit of Medical Protein Science, Lund University, Lund, Sweden, Department of Clinical Sciences, Unit of Islet Cell Exocytosis, Lund University Diabetes Centre, Malmö, Sweden

  https://orcid.org/0000-0002-4313-2666

  ⨯