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Open Access
Peer-reviewed
Research Article
Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy
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Niels R. C. Meijns ,
Contributed equally to this work with: Niels R. C. Meijns, Max Blokker
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
¶☯ These authors contributed equally to this work.
Affiliation Department of Anatomy and Neuroscience, Amsterdam UMC - location VUmc, Amsterdam Neuroscience, MS Center Amsterdam, The Netherlands
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Max Blokker ,
Contributed equally to this work with: Niels R. C. Meijns, Max Blokker
Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing
¶☯ These authors contributed equally to this work.
Affiliation LaserLaB, Faculty of Science, Department of Physics, Vrije Universiteit Amsterdam, The Netherlands
⨯ - Sander Idema,
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Bert A. ’t Hart,
Roles Conceptualization, Data curation, Writing – review & editing
Affiliation Department of Anatomy and Neuroscience, Amsterdam UMC - location VUmc, Amsterdam Neuroscience, MS Center Amsterdam, The Netherlands
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Mitko Veta,
Roles Methodology, Supervision
Affiliation Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands
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Loes Ettema,
Roles Data curation, Visualization
Affiliation LaserLaB, Faculty of Science, Department of Physics, Vrije Universiteit Amsterdam, The Netherlands
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Juliet van Iersel,
Roles Data curation, Visualization
Affiliation Department of Anatomy and Neuroscience, Amsterdam UMC - location VUmc, Amsterdam Neuroscience, MS Center Amsterdam, The Netherlands
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Zhiqing Zhang,
Roles Conceptualization, Supervision
Affiliation Department of Electronic Information and Optical Engineering, Nankai University, China
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Geert J. Schenk,
Roles Conceptualization, Methodology, Supervision, Writing – original draft, Writing – review & editing
Affiliation Department of Anatomy and Neuroscience, Amsterdam UMC - location VUmc, Amsterdam Neuroscience, MS Center Amsterdam, The Netherlands
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Marie Louise Groot ,
Roles Conceptualization, Data curation, Funding acquisition, Methodology, Writing – original draft, Writing – review & editing
* E-mail: a.luchicchi@amsterdamumc.nl (AL); m.groot@vu.nl (MLG)
¶‡ These authors also contributed equally to this work.
Affiliation LaserLaB, Faculty of Science, Department of Physics, Vrije Universiteit Amsterdam, The Netherlands
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Antonio Luchicchi
Roles Conceptualization, Data curation, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing
* E-mail: a.luchicchi@amsterdamumc.nl (AL); m.groot@vu.nl (MLG)
¶‡ These authors also contributed equally to this work.
Affiliation Department of Anatomy and Neuroscience, Amsterdam UMC - location VUmc, Amsterdam Neuroscience, MS Center Amsterdam, The Netherlands
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Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy
- Niels R. C. Meijns,
- Max Blokker,
- Sander Idema,
- Bert A. ’t Hart,
- Mitko Veta,
- Loes Ettema,
- Juliet van Iersel,
- Zhiqing Zhang,
- Geert J. Schenk,
- Marie Louise Groot
- Published: March 31, 2025
- https://doi.org/10.1371/journal.pone.0310663