TRPML1 acts as a predisposing factor in lymphedema development by regulating the subcellular localization of aquaporin-3, -5

Lijie Yang; Guanzheng Wang; Yuan Ma; Qiancheng Zhao; He Zhao; Qi Wang; Chonghua Zhong; Chunmei Zhang; Yiming Yang

doi:10.1371/journal.pone.0310653

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Open Access

Peer-reviewed

Research Article

TRPML1 acts as a predisposing factor in lymphedema development by regulating the subcellular localization of aquaporin-3, -5

Lijie Yang,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Department of Cell Biology and Medical Genetics, College of Basic Medical Sciences, Jilin University, Changchun, Jilin Province, China
⨯
Guanzheng Wang,

Roles Data curation, Methodology, Visualization

Affiliation Department of Cell Biology and Medical Genetics, College of Basic Medical Sciences, Jilin University, Changchun, Jilin Province, China
⨯
Yuan Ma,

Roles Data curation

Affiliation College of Basic Medicine, Changchun University of Chinese Medicine, Changchun, Jilin Province, China
⨯
Qiancheng Zhao,

Roles Data curation, Methodology

Affiliation Department of Cell Biology and Medical Genetics, College of Basic Medical Sciences, Jilin University, Changchun, Jilin Province, China
⨯
He Zhao,

Roles Data curation

Affiliation Department of Cell Biology and Medical Genetics, College of Basic Medical Sciences, Jilin University, Changchun, Jilin Province, China
⨯
Qi Wang,

Roles Data curation

Affiliation Department of Cell Biology and Medical Genetics, College of Basic Medical Sciences, Jilin University, Changchun, Jilin Province, China
⨯
Chonghua Zhong,

Roles Methodology

Affiliation College of Basic Medical Sciences, Jilin University, Changchun, Jilin Province, China
⨯
Chunmei Zhang ,

Roles Project administration, Supervision

* E-mail: zhangcm499@jlu.edu.cn (CZ); ym_yang@jlu.edu.cn (YY)

Affiliation Department of Cell Biology and Medical Genetics, College of Basic Medical Sciences, Jilin University, Changchun, Jilin Province, China
⨯
Yiming Yang

Roles Conceptualization, Funding acquisition, Supervision

* E-mail: zhangcm499@jlu.edu.cn (CZ); ym_yang@jlu.edu.cn (YY)

Affiliations Department of Cell Biology and Medical Genetics, College of Basic Medical Sciences, Jilin University, Changchun, Jilin Province, China, College of Basic Medical Sciences, Jilin University, Changchun, Jilin Province, China

https://orcid.org/0000-0002-6716-8014

⨯

TRPML1 acts as a predisposing factor in lymphedema development by regulating the subcellular localization of aquaporin-3, -5

Lijie Yang,
Guanzheng Wang,
Yuan Ma,
Qiancheng Zhao,
He Zhao,
Qi Wang,
Chonghua Zhong,
Chunmei Zhang,
Yiming Yang

Published: December 5, 2024
https://doi.org/10.1371/journal.pone.0310653

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Mouse models
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Cell membranes
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