CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting

• Kelly Lim,

  Roles Conceptualization, Formal analysis, Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliations Discipline of Medicine, Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia, Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide, Adelaide, SA, Australia

  https://orcid.org/0000-0003-4606-7588

  ⨯
• Winnie L. Kan,

  Roles Formal analysis, Writing – review & editing

  Affiliation Cytokine Receptor Laboratory, SA Pathology, Adelaide, SA, Australia

  https://orcid.org/0000-0002-5844-7644

  ⨯
• Pramod C. Nair,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Discipline of Medicine, Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia, Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide, Adelaide, SA, Australia, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia

  https://orcid.org/0000-0002-8630-0121

  ⨯
• Monika Kutyna,

  Roles Methodology

  Affiliations Discipline of Medicine, Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia, Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide, Adelaide, SA, Australia

  ⨯
• Angel F. Lopez,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliations Discipline of Medicine, Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia, Cytokine Receptor Laboratory, SA Pathology, Adelaide, SA, Australia

  ⨯
• Timothy Hercus,

  Roles Funding acquisition

  Affiliation Cytokine Receptor Laboratory, SA Pathology, Adelaide, SA, Australia

  https://orcid.org/0000-0001-5290-9206

  ⨯
• David M. Ross,

  Roles Funding acquisition, Writing – review & editing

  Affiliations Discipline of Medicine, Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia, Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide, Adelaide, SA, Australia, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia, SA Pathology, Adelaide, SA, Australia, Department of Hematology and Bone Marrow Transplantation, Royal Adelaide Hospital, Adelaide, SA, Australia

  ⨯
• Steven Lane,

  Roles Funding acquisition

  Affiliation QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia

  ⨯
• Chun Yew Fong,

  Roles Funding acquisition

  Affiliation Austin Health, Heidelberg, VIC, Australia

  https://orcid.org/0000-0001-5773-103X

  ⨯
• Anna Brown,

  Roles Funding acquisition

  Affiliation SA Pathology, Adelaide, SA, Australia

  ⨯
• Agnes Yong,

  Roles Funding acquisition

  Affiliations Discipline of Medicine, Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia, Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide, Adelaide, SA, Australia, Royal Perth Hospital, Perth, WA, Australia, The University of Western Australia Medical School, Perth, WA, Australia

  ⨯
• David Yeung,

  Roles Funding acquisition

  Affiliations Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide, Adelaide, SA, Australia, Department of Hematology and Bone Marrow Transplantation, Royal Adelaide Hospital, Adelaide, SA, Australia

  ⨯
• Timothy Hughes,

  Roles Funding acquisition

  Affiliation Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide, Adelaide, SA, Australia

  ⨯
• Devendra Hiwase,

  Roles Funding acquisition, Writing – review & editing

  Affiliations Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide, Adelaide, SA, Australia, SA Pathology, Adelaide, SA, Australia, Department of Hematology and Bone Marrow Transplantation, Royal Adelaide Hospital, Adelaide, SA, Australia

  ⨯
• Daniel Thomas

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

  * E-mail: daniel.thomas@adelaide.edu.au

  Affiliations Discipline of Medicine, Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia, Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide, Adelaide, SA, Australia, SA Pathology, Adelaide, SA, Australia, Department of Hematology and Bone Marrow Transplantation, Royal Adelaide Hospital, Adelaide, SA, Australia

  https://orcid.org/0000-0002-0837-1231

  ⨯