The effects of secretome of umbilical cord mesenchymal stem cells on regeneration of sciatic nerve defects in Sprague dawley rats

Aryadi Kurniawan; Ismail Hadisoebroto Dilogo; Jeanne Adiwinata Pawitan; Wahyu Widodo; Ihsan Oesman; Ade Martinus

doi:10.1371/journal.pone.0310467

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Open Access

Peer-reviewed

Research Article

The effects of secretome of umbilical cord mesenchymal stem cells on regeneration of sciatic nerve defects in Sprague dawley rats

Aryadi Kurniawan,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Validation, Writing – review & editing

Affiliation Faculty of Medicine Universitas Indonesia, Department of Orthopaedics & Traumatology, Dr Cipto Mangunkusumo National Central Hospital, Jakarta, Indonesia
⨯
Ismail Hadisoebroto Dilogo,

Roles Conceptualization, Investigation, Supervision, Validation, Writing – review & editing

Affiliations Faculty of Medicine Universitas Indonesia, Department of Orthopaedics & Traumatology, Dr Cipto Mangunkusumo National Central Hospital, Jakarta, Indonesia, Stem Cell Medical Technology Integrated Service Unit, Dr Cipto Mangunkusumo National Central Hospital, Jakarta, Indonesia
⨯
Jeanne Adiwinata Pawitan,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Validation

Affiliation Faculty of Medicine Universitas Indonesia, Department of Histology, Dr Cipto Mangunkusumo National Central Hospital, Jakarta, Indonesia
⨯
Wahyu Widodo,

Roles Conceptualization, Data curation, Formal analysis, Project administration, Supervision, Writing – review & editing

Affiliation Faculty of Medicine Universitas Indonesia, Department of Orthopaedics & Traumatology, Dr Cipto Mangunkusumo National Central Hospital, Jakarta, Indonesia
⨯
Ihsan Oesman,

Roles Investigation, Project administration, Resources, Supervision, Writing – review & editing

Affiliation Faculty of Medicine Universitas Indonesia, Department of Orthopaedics & Traumatology, Dr Cipto Mangunkusumo National Central Hospital, Jakarta, Indonesia
⨯
Ade Martinus

Roles Conceptualization, Data curation, Formal analysis, Writing – original draft, Writing – review & editing

* E-mail: orthoademartinus@gmail.com

Affiliation Faculty of Medicine Universitas Indonesia, Department of Orthopaedics & Traumatology, Dr Cipto Mangunkusumo National Central Hospital, Jakarta, Indonesia

https://orcid.org/0009-0002-0470-5537

⨯

The effects of secretome of umbilical cord mesenchymal stem cells on regeneration of sciatic nerve defects in Sprague dawley rats

Aryadi Kurniawan,
Ismail Hadisoebroto Dilogo,
Jeanne Adiwinata Pawitan,
Wahyu Widodo,
Ihsan Oesman,
Ade Martinus

Published: December 31, 2024
https://doi.org/10.1371/journal.pone.0310467

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Sciatic nerves
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Gastrocnemius muscles
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Nerve regeneration
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Umbilical cord
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