Integrated metagenomic and metabonomic mechanisms for the therapeutic effects of Duhuo Jisheng decoction on intervertebral disc degeneration

• Chao Song ,

  Contributed equally to this work with: Chao Song, Fei Liu

  Roles Writing – original draft

  Affiliation Department of Orthopedics and Traumatology (Trauma and Bone-Setting), The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China

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• Fei Liu ,

  Contributed equally to this work with: Chao Song, Fei Liu

  Roles Writing – review & editing

  Affiliation Department of Orthopedics and Traumatology (Trauma and Bone-Setting), The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China

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• Yongliang Mei,

  Roles Formal analysis

  Affiliation Department of Orthopedics and Traumatology (Trauma and Bone-Setting), The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China

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• Weiye Cai,

  Roles Formal analysis, Methodology

  Affiliation Department of Orthopedics and Traumatology (Trauma and Bone-Setting), The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China

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• Kang Cheng,

  Roles Resources, Software

  Affiliation Department of Orthopedics and Traumatology (Trauma and Bone-Setting), The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China

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• Daru Guo,

  Roles Validation

  Affiliation Department of Orthopedics and Traumatology (Trauma and Bone-Setting), The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China

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• Yong Liu,

  Roles Resources

  Affiliation Department of Orthopedics and Traumatology (Trauma and Bone-Setting), The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China

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• Houyin Shi,

  Roles Formal analysis, Methodology

  Affiliation Department of Orthopedics and Traumatology (Trauma and Bone-Setting), The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China

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• Dayue Darrel Duan ,

  Roles Conceptualization, Writing – review & editing

  * E-mail: dduan@swmu.edu.cn (DDD); lzcxnykdx@swmu.edu.cn (ZL)

  Current address: Longmatan District, Luzhou City, Sichuan Province, China

  Affiliation Center for Phenomics of Traditional Chinese Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China

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• Zongchao Liu

  Roles Conceptualization

  * E-mail: dduan@swmu.edu.cn (DDD); lzcxnykdx@swmu.edu.cn (ZL)

  Current address: Longmatan District, Luzhou City, Sichuan Province, China

  Affiliations Department of Orthopedics and Traumatology (Trauma and Bone-Setting), The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China, Luzhou Longmatan District People’s Hospital, Luzhou, Sichuan Province, China

  https://orcid.org/0000-0002-7101-1765

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