Mechanism of MiR-145a-3p/Runx2 pathway in dexamethasone impairment of MC3T3-E1 osteogenic capacity in mice

Hang Wu; Xinghua Liao; Tingrui Wu; Bin Xie; Sicheng Ding; Yiren Chen; Lijun Song; Bo Wei

doi:10.1371/journal.pone.0309951

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Open Access

Peer-reviewed

Research Article

Mechanism of MiR-145a-3p/Runx2 pathway in dexamethasone impairment of MC3T3-E1 osteogenic capacity in mice

Hang Wu ,

Contributed equally to this work with: Hang Wu, Xinghua Liao

Roles Software, Writing – original draft, Writing – review & editing

Affiliation Orthopedics Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China

https://orcid.org/0009-0009-0589-5396

⨯
Xinghua Liao ,

Contributed equally to this work with: Hang Wu, Xinghua Liao

Roles Project administration, Resources, Software

Affiliation Central People’s Hospital of Zhanjiang, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China
⨯
Tingrui Wu,

Roles Conceptualization, Data curation, Formal analysis

Affiliation Orthopedics Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China
⨯
Bin Xie,

Roles Investigation, Methodology, Project administration

Affiliation Orthopedics Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China
⨯
Sicheng Ding,

Roles Formal analysis

Affiliation Orthopedics Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China
⨯
Yiren Chen,

Roles Methodology, Project administration

Affiliation Orthopedics Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China
⨯
Lijun Song ,

Roles Formal analysis, Funding acquisition, Investigation

* E-mail: lijunsong0369@163.com (LS); webjxmc@163.com (BW)

Affiliation Reproductive Medicine Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China
⨯
Bo Wei

Roles Funding acquisition, Project administration, Resources, Software, Supervision, Validation, Visualization

* E-mail: lijunsong0369@163.com (LS); webjxmc@163.com (BW)

Affiliation Orthopedics Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China
⨯

Mechanism of MiR-145a-3p/Runx2 pathway in dexamethasone impairment of MC3T3-E1 osteogenic capacity in mice

Hang Wu,
Xinghua Liao,
Tingrui Wu,
Bin Xie,
Sicheng Ding,
Yiren Chen,
Lijun Song,
Bo Wei

Published: November 19, 2024
https://doi.org/10.1371/journal.pone.0309951

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