Maggot extract accelerates skin wound healing of diabetic rats via enhancing STAT3 signaling

Mo-Li Wu; Zhe-Ming Yang; Hai-Chao Dong; Hong Zhang; Xu Zheng; Bo Yuan; Yang Yang; Jia Liu; Pei-Nan Li

doi:10.1371/journal.pone.0309903

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Open Access

Peer-reviewed

Research Article

Maggot extract accelerates skin wound healing of diabetic rats via enhancing STAT3 signaling

Mo-Li Wu ,

Contributed equally to this work with: Mo-Li Wu, Zhe-Ming Yang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Cell Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China
⨯
Zhe-Ming Yang ,

Contributed equally to this work with: Mo-Li Wu, Zhe-Ming Yang

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Cell Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China
⨯
Hai-Chao Dong,

Roles Formal analysis

Affiliation Department of Orthopedic Surgery, Second Affiliated Hospital, Dalian Medical University, Dalian, China
⨯
Hong Zhang,

Roles Data curation

Affiliation Department of Orthopedic Surgery, Second Affiliated Hospital, Dalian Medical University, Dalian, China
⨯
Xu Zheng,

Roles Investigation

Affiliation Department of Cell Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China
⨯
Bo Yuan,

Roles Investigation

Affiliations Department of Cell Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China, Department of Orthopedic Surgery, Second Affiliated Hospital, Dalian Medical University, Dalian, China
⨯
Yang Yang,

Roles Investigation

Affiliation Department of Cell Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China
⨯
Jia Liu ,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: jialiudl2022@163.com (JL); lipndl@163.com (PNL)

Affiliation Department of Cell Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China

https://orcid.org/0009-0004-9275-6506

⨯
Pei-Nan Li

Roles Conceptualization, Data curation, Funding acquisition, Supervision

* E-mail: jialiudl2022@163.com (JL); lipndl@163.com (PNL)

Affiliation Department of Orthopedic Surgery, Second Affiliated Hospital, Dalian Medical University, Dalian, China
⨯

Maggot extract accelerates skin wound healing of diabetic rats via enhancing STAT3 signaling

Mo-Li Wu,
Zhe-Ming Yang,
Hai-Chao Dong,
Hong Zhang,
Xu Zheng,
Bo Yuan,
Yang Yang,
Jia Liu,
Pei-Nan Li

Published: September 6, 2024
https://doi.org/10.1371/journal.pone.0309903

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Diabetes mellitus
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Wound healing
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Blood sugar
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STAT signaling
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Granulation tissue
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Cyclins
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Immunofluorescence staining
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Immunohistochemistry techniques
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