Dual inhibition of oxidative phosphorylation and glycolysis exerts a synergistic antitumor effect on colorectal and gastric cancer by creating energy depletion and preventing metabolic switch

• Yuki Aisu,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft

  Affiliation Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

  https://orcid.org/0000-0002-5168-8664

  ⨯
• Nobu Oshima ,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: noshima@kuhp.kyoto-u.ac.jp

  Affiliations Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan, Department of Surgery, Kobe City Medical Center General Hospital, Kobe, Japan

  https://orcid.org/0000-0003-2178-5241

  ⨯
• Fuminori Hyodo,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Software, Visualization, Writing – review & editing

  Affiliations Department of Radiology, Gifu University Hospital, Gifu, Japan, Department of Radiology, Frontier Science for Imaging, Gifu University, Gifu, Japan

  ⨯
• Abdelazim Elsayed Elhelaly,

  Roles Data curation, Formal analysis, Investigation, Resources, Software, Visualization, Writing – review & editing

  Affiliation Department of Radiology, Frontier Science for Imaging, Gifu University, Gifu, Japan

  ⨯
• Akihiko Masuo,

  Roles Investigation, Methodology

  Affiliation Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Tomoaki Okada,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Shigeo Hisamori,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Shigeru Tsunoda,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Koya Hida,

  Roles Writing – review & editing

  Affiliation Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Tomonori Morimoto,

  Roles Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

  https://orcid.org/0000-0003-0535-0889

  ⨯
• Hiroyuki Miyoshi,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Colon Cancer Project, Kyoto University Hospital-iACT, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Makoto M. Taketo,

  Roles Resources, Writing – review & editing

  Affiliation Colon Cancer Project, Kyoto University Hospital-iACT, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Masayuki Matsuo,

  Roles Resources, Software, Supervision, Visualization, Writing – review & editing

  Affiliation Department of Radiology, Gifu University Hospital, Gifu, Japan

  ⨯
• Leonard M. Neckers,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation National Cancer Institute, Urologic Oncology Branch, Center for Cancer Research, NIH, Bethesda, Maryland, United States of America

  ⨯
• Yoshiharu Sakai,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Gastrointestinal Surgery, Osaka Red Cross Hospital, Osaka, Japan

  ⨯
•  [ ... ],
• Kazutaka Obama

  Roles Supervision, Writing – review & editing

  Affiliation Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

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