Development of methodology to support molecular endotype discovery from synovial fluid of individuals with knee osteoarthritis: The STEpUP OA consortium

• Yun Deng ,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  ¶‡ YD and TAP are joint first authors on this work.

  Affiliation Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, United Kingdom

  ⨯
• Thomas A. Perry ,

  Roles Data curation, Formal analysis, Methodology, Project administration, Writing – original draft, Writing – review & editing

  ¶‡ YD and TAP are joint first authors on this work.

  Affiliation Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, United Kingdom

  https://orcid.org/0000-0002-0499-3033

  ⨯
• Philippa Hulley,

  Roles Methodology, Writing – review & editing

  Affiliation Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom

  https://orcid.org/0000-0002-4994-2264

  ⨯
• Rose A. Maciewicz,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, United Kingdom

  ⨯
• Joanna Mitchelmore,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation Novartis Institutes for Biomedical Research, Basel, Switzerland

  ⨯
• Darryl Perry,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation SomaLogic, Boulder, Colorado, United States of America

  ⨯
• Staffan Larsson,

  Roles Writing – review & editing

  Affiliation Department of Clinical Sciences Lund, Orthopaedics, Faculty of Medicine, Lund University, Lund, Sweden

  https://orcid.org/0000-0001-8626-9892

  ⨯
• Sophie Brachat,

  Roles Methodology, Writing – review & editing

  Affiliation Novartis Institutes for Biomedical Research, Basel, Switzerland

  ⨯
• André Struglics,

  Roles Writing – review & editing

  Affiliation Department of Clinical Sciences Lund, Orthopaedics, Faculty of Medicine, Lund University, Lund, Sweden

  https://orcid.org/0000-0003-4289-1393

  ⨯
• C. Thomas Appleton,

  Roles Resources, Writing – review & editing

  Affiliation Bone and Joint Institute, University of Western Ontario, London, Ontario, Canada

  ⨯
• Stefan Kluzek,

  Roles Resources, Writing – review & editing

  Affiliations Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, NIHR Nottingham Biomedical Research Centre and Versus Arthritis Sport, Exercise and Osteoarthritis Centre, University of Nottingham, Nottingham, United Kingdom

  ⨯
• Nigel K. Arden,

  Roles Resources, Writing – review & editing

  Affiliations Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, Centre for Sport, Exercise and Osteoarthritis Research Versus Arthritis, University of Oxford, Oxford, United Kingdom

  ⨯
• David Felson,

  Roles Writing – review & editing

  Affiliation Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, United States of America

  ⨯
• Brian Marsden,

  Roles Data curation, Project administration, Software, Writing – review & editing

  Affiliations Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

  ⨯
• Brian D. M. Tom,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation MRC Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Laura Bondi,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation MRC Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom

  https://orcid.org/0000-0002-7034-9406

  ⨯
• Mohit Kapoor,

  Roles Resources, Writing – review & editing

  Affiliation Schroeder Arthritis Institute, University Health Network, Toronto, Ontario, Canada

  ⨯
• Vicky Batchelor,

  Roles Methodology, Project administration, Writing – review & editing

  Affiliation Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, United Kingdom

  ⨯
• Jennifer Mackay-Alderson,

  Roles Methodology, Project administration, Writing – review & editing

  Affiliation Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, United Kingdom

  ⨯
• Vinod Kumar,

  Roles Data curation, Project administration, Software, Writing – review & editing

  Affiliation Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom

  ⨯
• L. Stefan Lohmander,

  Roles Resources, Writing – review & editing

  Affiliation Department of Clinical Sciences Lund, Orthopaedics, Faculty of Medicine, Lund University, Lund, Sweden

  https://orcid.org/0000-0002-5424-9448

  ⨯
• Tim J. Welting,

  Roles Resources, Writing – review & editing

  Affiliation Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery, Maastricht University, Maastricht, Netherlands

  ⨯
• David A. Walsh,

  Roles Resources, Writing – review & editing

  Affiliations Pain Centre Versus Arthritis, Advanced Pain Discovery Platform, and the NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom, Sherwood Forest Hospitals NHS Foundation Trust, Sutton in Ashfield, United Kingdom

  https://orcid.org/0000-0002-6316-5692

  ⨯
• Ana M. Valdes,

  Roles Resources, Writing – review & editing

  Affiliation Pain Centre Versus Arthritis, Advanced Pain Discovery Platform, and the NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom

  ⨯
• the STEpUP OA Consortium ,

  ¶Membership of the STEpUP OA Consortium is provided in the STEpUP OA Consortium author block section of the manuscript.

  ⨯
• Tonia L. Vincent ,

  Contributed equally to this work with: Tonia L. Vincent, Fiona E. Watt, Luke Jostins-Dean

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: tonia.vincent@kennedy.ox.ac.uk

  Affiliation Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, United Kingdom

  ⨯
• Fiona E. Watt ,

  Contributed equally to this work with: Tonia L. Vincent, Fiona E. Watt, Luke Jostins-Dean

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, United Kingdom, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom

  ⨯
•  [ ... ],
• Luke Jostins-Dean

  Contributed equally to this work with: Tonia L. Vincent, Fiona E. Watt, Luke Jostins-Dean

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, United Kingdom

  ⨯
• [ view all ]
• [ view less ]