Survivin inhibition attenuates EGF-induced epithelial mesenchymal transformation of human RPE cells via the EGFR/MAPK pathway

• Yusheng Zhu ,

  Contributed equally to this work with: Yusheng Zhu, Teng Li

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Faculty of Life Sciences and medicine, Northwest University, Xi’an, Shaanxi Province, China, First Affiliated Hospital of Northwest University, Northwest University, Xi’an, Shaanxi Province, China, Department of Ophthalmology, Xi’an No.1 Hospital, Xi’an, Shaanxi Province, China, Shaanxi Institute of Ophthalmology, Shaanxi Provincial Key Lab of Ophthalmology, Clinical Research Center for Ophthalmology Diseases of Shaanxi Province, Xi’an, Shaanxi Province, China

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• Teng Li ,

  Contributed equally to this work with: Yusheng Zhu, Teng Li

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Visualization

  Affiliations Faculty of Life Sciences and medicine, Northwest University, Xi’an, Shaanxi Province, China, First Affiliated Hospital of Northwest University, Northwest University, Xi’an, Shaanxi Province, China, Department of Ophthalmology, Xi’an No.1 Hospital, Xi’an, Shaanxi Province, China, Shaanxi Institute of Ophthalmology, Shaanxi Provincial Key Lab of Ophthalmology, Clinical Research Center for Ophthalmology Diseases of Shaanxi Province, Xi’an, Shaanxi Province, China

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• Sirui Zhou,

  Roles Data curation, Visualization

  Affiliations Faculty of Life Sciences and medicine, Northwest University, Xi’an, Shaanxi Province, China, First Affiliated Hospital of Northwest University, Northwest University, Xi’an, Shaanxi Province, China, Department of Ophthalmology, Xi’an No.1 Hospital, Xi’an, Shaanxi Province, China, Shaanxi Institute of Ophthalmology, Shaanxi Provincial Key Lab of Ophthalmology, Clinical Research Center for Ophthalmology Diseases of Shaanxi Province, Xi’an, Shaanxi Province, China

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• Guowei Wang,

  Roles Formal analysis

  Affiliation Faculty of Life Sciences and medicine, Northwest University, Xi’an, Shaanxi Province, China

  ⨯
• Huihui Zhang,

  Roles Investigation

  Affiliations Faculty of Life Sciences and medicine, Northwest University, Xi’an, Shaanxi Province, China, First Affiliated Hospital of Northwest University, Northwest University, Xi’an, Shaanxi Province, China, Department of Ophthalmology, Xi’an No.1 Hospital, Xi’an, Shaanxi Province, China, Shaanxi Institute of Ophthalmology, Shaanxi Provincial Key Lab of Ophthalmology, Clinical Research Center for Ophthalmology Diseases of Shaanxi Province, Xi’an, Shaanxi Province, China

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• Yong Yin,

  Roles Resources, Supervision

  Affiliation Xi’ an Eye Bank, Xi’an No.1 Hospital, Xi’an, Shaanxi Province, China

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• Tong Wang,

  Roles Project administration, Resources, Supervision

  Affiliations Faculty of Life Sciences and medicine, Northwest University, Xi’an, Shaanxi Province, China, First Affiliated Hospital of Northwest University, Northwest University, Xi’an, Shaanxi Province, China, Department of Ophthalmology, Xi’an No.1 Hospital, Xi’an, Shaanxi Province, China, Shaanxi Institute of Ophthalmology, Shaanxi Provincial Key Lab of Ophthalmology, Clinical Research Center for Ophthalmology Diseases of Shaanxi Province, Xi’an, Shaanxi Province, China

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• Xiaodong Chen

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Software, Supervision, Writing – review & editing

  * E-mail: 390203850@qq.com

  Affiliations Faculty of Life Sciences and medicine, Northwest University, Xi’an, Shaanxi Province, China, First Affiliated Hospital of Northwest University, Northwest University, Xi’an, Shaanxi Province, China, Department of Ophthalmology, Xi’an No.1 Hospital, Xi’an, Shaanxi Province, China, Shaanxi Institute of Ophthalmology, Shaanxi Provincial Key Lab of Ophthalmology, Clinical Research Center for Ophthalmology Diseases of Shaanxi Province, Xi’an, Shaanxi Province, China

  https://orcid.org/0000-0002-4708-0058

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