Knockout of the orphan membrane transporter Slc22a23 leads to a lean and hyperactive phenotype with a small hippocampal volume

• Yasuhiro Uchimura ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: uchimura@belle.shiga-med.ac.jp (YU); udagawa@belle.shiga-med.ac.jp (JU)

  Affiliation Division of Anatomy and Cell Biology, Department of Anatomy, Shiga University of Medical Science, Otsu, Shiga, Japan

  https://orcid.org/0000-0001-8633-2468

  ⨯
• Kodai Hino †,

  † Deceased.

  Roles Investigation

  Affiliation Division of Anatomy and Cell Biology, Department of Anatomy, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯
• Kosuke Hattori,

  Roles Investigation, Methodology, Resources

  Affiliation Division of Animal Genetics, Laboratory Animal Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan

  ⨯
• Yoshinori Kubo,

  Roles Investigation

  Affiliation Division of Anatomy and Cell Biology, Department of Anatomy, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯
• Airi Owada,

  Roles Investigation

  Affiliation Division of Anatomy and Cell Biology, Department of Anatomy, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯
• Tomoko Kimura,

  Roles Investigation

  Affiliation Division of Anatomy and Cell Biology, Department of Anatomy, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯
• Lucia Sugawara,

  Roles Investigation, Methodology, Resources

  Affiliation Department of Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯
• Shinji Kume,

  Roles Investigation, Resources, Supervision

  Affiliation Department of Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯
• Jean-Pierre Bellier,

  Roles Investigation, Methodology, Resources

  Current address: Department of Neurology, Brigham and Women’s Hospital/Harvard Medical School, Cambridge, MA, United States of America

  Affiliation Molecular Neuroscience Research Center, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯
• Daijiro Yanagisawa,

  Roles Investigation, Methodology, Resources

  Affiliation Molecular Neuroscience Research Center, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯
• Akihiko Shiino,

  Roles Investigation, Methodology, Resources

  Affiliation Molecular Neuroscience Research Center, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯
• Takahisa Nakayama,

  Roles Investigation, Methodology, Resources

  Affiliation Division of Human Pathology, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯
• Yataro Daigo,

  Roles Funding acquisition, Investigation, Methodology, Resources, Supervision

  Affiliation Department of Medical Oncology, Cancer Center and Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯
• Tomoji Mashimo,

  Roles Funding acquisition, Investigation, Methodology, Resources, Supervision

  Affiliation Division of Animal Genetics, Laboratory Animal Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan

  ⨯
• Jun Udagawa

  Roles Conceptualization, Investigation, Supervision, Writing – review & editing

  * E-mail: uchimura@belle.shiga-med.ac.jp (YU); udagawa@belle.shiga-med.ac.jp (JU)

  Affiliation Division of Anatomy and Cell Biology, Department of Anatomy, Shiga University of Medical Science, Otsu, Shiga, Japan

  ⨯