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Open Access
Peer-reviewed
Research Article
Impact of variable titer COVID-19 convalescent plasma and recipient SARS-CoV2-specific humoral immunity on survival in hospitalized patients
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Carlo J. Iasella,
Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania, United States of America
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Stefanie J. Hannan,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Emily J. Lyons,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Sophia C. Lieber,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Antu Das,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Dimiter Dimitrov,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Medicine, Aging Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Wei Li,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Medicine, Aging Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Melissa Saul,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Iulia Popescu,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Ritchie Koshy,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Robin Burke,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Braidon Lape,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania, United States of America
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Mark J. Brown,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Xiaoping Chen,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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John C. Sembrat,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Kaitlyn Devonshire,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Georgios D. Kitsios,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Ioannis Konstantinidis,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Mark E. Snyder,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Bill B. Chen,
Roles Investigation, Methodology, Writing – review & editing
Affiliations Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Christian A. Merlo,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America
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David N. Hager,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America
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Joseph E. Kiss,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Pathology, Division of Transfusion Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Mark H. Yazer,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Pathology, Division of Transfusion Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Alan H. Wells,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Pathology, Division of Laboratory Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Alison Morris,
Roles Conceptualization, Formal analysis, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Bryan J. McVerry,
Roles Conceptualization, Formal analysis, Writing – review & editing
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Deborah K. McMahon,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Medicine, Aging Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Darrell J. Triulzi,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Pathology, Division of Transfusion Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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John F. McDyer
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing
* E-mail: mcdyerjf@upmc.edu
Affiliation Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Impact of variable titer COVID-19 convalescent plasma and recipient SARS-CoV2-specific humoral immunity on survival in hospitalized patients
- Carlo J. Iasella,
- Stefanie J. Hannan,
- Emily J. Lyons,
- Sophia C. Lieber,
- Antu Das,
- Dimiter Dimitrov,
- Wei Li,
- Melissa Saul,
- Iulia Popescu,
- Ritchie Koshy
- Published: October 24, 2024
- https://doi.org/10.1371/journal.pone.0309449