Upregulation of Metrnl improves diabetic kidney disease by inhibiting the TGF-β1/Smads signaling pathway: A potential therapeutic target

Lu Lin; Shulin Huang; Xin Lin; Xiaoling Liu; Xiangjin Xu; Chunmei Li; Pin Chen

doi:10.1371/journal.pone.0309338

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Open Access

Peer-reviewed

Research Article

Upregulation of Metrnl improves diabetic kidney disease by inhibiting the TGF-β1/Smads signaling pathway: A potential therapeutic target

Lu Lin ,

Contributed equally to this work with: Lu Lin, Shulin Huang, Xin Lin

Roles Conceptualization, Formal analysis, Writing – original draft

Affiliation 900TH Hospital of Joint Logistic Support Force (Fuzong Clinical Medical College of Fujian Medical University), Fuzhou, China
⨯
Shulin Huang ,

Contributed equally to this work with: Lu Lin, Shulin Huang, Xin Lin

Roles Formal analysis, Writing – review & editing

Affiliation 900TH Hospital of Joint Logistic Support Force (Fuzong Clinical Medical College of Fujian Medical University), Fuzhou, China
⨯
Xin Lin ,

Contributed equally to this work with: Lu Lin, Shulin Huang, Xin Lin

Roles Conceptualization, Investigation, Methodology, Writing – original draft

Affiliation 900TH Hospital of Joint Logistic Support Force (Fuzong Clinical Medical College of Fujian Medical University), Fuzhou, China
⨯
Xiaoling Liu,

Roles Methodology, Writing – review & editing

Affiliation 900TH Hospital of Joint Logistic Support Force (Fuzong Clinical Medical College of Fujian Medical University), Fuzhou, China
⨯
Xiangjin Xu,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliation 900TH Hospital of Joint Logistic Support Force (Fuzong Clinical Medical College of Fujian Medical University), Fuzhou, China
⨯
Chunmei Li,

Roles Methodology, Writing – original draft

Affiliation 900TH Hospital of Joint Logistic Support Force (Fuzong Clinical Medical College of Fujian Medical University), Fuzhou, China
⨯
Pin Chen

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

* E-mail: chenpin@21cn.com

Affiliation 900TH Hospital of Joint Logistic Support Force (Fuzong Clinical Medical College of Fujian Medical University), Fuzhou, China

https://orcid.org/0000-0002-6219-9591

⨯

Upregulation of Metrnl improves diabetic kidney disease by inhibiting the TGF-β1/Smads signaling pathway: A potential therapeutic target

Lu Lin,
Shulin Huang,
Xin Lin,
Xiaoling Liu,
Xiangjin Xu,
Chunmei Li,
Pin Chen

Published: August 27, 2024
https://doi.org/10.1371/journal.pone.0309338

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