Identification of breast cancer-associated PIK3CA H1047R mutation in blood circulation using an asymmetric PCR assay

Dinh Thi Thao; Nguyen Phu Thanh; Dong Van Quyen; Ly Tuan Khai; Le Huu Song; Ngo Tat Trung

doi:10.1371/journal.pone.0309209

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Open Access

Peer-reviewed

Research Article

Identification of breast cancer-associated PIK3CA H1047R mutation in blood circulation using an asymmetric PCR assay

Dinh Thi Thao ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: tatrungngo@gmail.com (NTT); thaodinh3883@gmail.com (DTT)

Affiliations Center for Genetic Consultation and Cancer Screening, 108 Military Center Hospital, Hai Ba Trung, Hanoi, Vietnam, University of Science and Technology of Hanoi, Cau Giay, Hanoi, Vietnam

https://orcid.org/0009-0002-4749-2949

⨯
Nguyen Phu Thanh,

Roles Data curation, Formal analysis, Investigation, Software, Validation

Affiliation Center for Genetic Consultation and Cancer Screening, 108 Military Center Hospital, Hai Ba Trung, Hanoi, Vietnam
⨯
Dong Van Quyen,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliations University of Science and Technology of Hanoi, Cau Giay, Hanoi, Vietnam, Institute of Biotechnology, Vietnam Academy of Science and Technology, Cau Giay, Hanoi, Vietnam
⨯
Ly Tuan Khai,

Roles Data curation, Resources, Writing – review & editing

Affiliation Department of Hematology, Laboratory Center, 108 Military Center Hospital, Hai Ba Trung, Hanoi, Vietnam
⨯
Le Huu Song,

Roles Conceptualization, Formal analysis, Methodology, Resources, Supervision, Writing – review & editing

Affiliation Vietnamese-German Center for Medical Research, 108 Military Center Hospital, Hai Ba Trung Hanoi, Vietnam
⨯
Ngo Tat Trung

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: tatrungngo@gmail.com (NTT); thaodinh3883@gmail.com (DTT)

Affiliations Center for Genetic Consultation and Cancer Screening, 108 Military Center Hospital, Hai Ba Trung, Hanoi, Vietnam, Vietnamese-German Center for Medical Research, 108 Military Center Hospital, Hai Ba Trung Hanoi, Vietnam

https://orcid.org/0000-0001-9808-1176

⨯

Identification of breast cancer-associated PIK3CA H1047R mutation in blood circulation using an asymmetric PCR assay

Dinh Thi Thao,
Nguyen Phu Thanh,
Dong Van Quyen,
Ly Tuan Khai,
Le Huu Song,
Ngo Tat Trung

Published: August 28, 2024
https://doi.org/10.1371/journal.pone.0309209

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Polymerase chain reaction
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Breast cancer
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Brain metastasis
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Mutation detection
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Point mutation
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Cancer treatment
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Blood plasma
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