Computational analysis of the deleterious non-synonymous single nucleotide polymorphisms (nsSNPs) in TYR gene impacting human tyrosinase protein and the protein stability

• Wei Fan ,

  Roles Conceptualization

  ¶‡ WF and HLJ contributed equally to this work and share the first authorship.

  Affiliation Department of Laboratory Medicine, Huaian Cancer Hospital, Huaian, Jiangsu, China

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• Heng Li Ji ,

  Roles Data curation, Investigation

  ¶‡ WF and HLJ contributed equally to this work and share the first authorship.

  Affiliation Nephrology Department, Huaian Cancer Hospital, Huaian, Jiangsu, China

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• Mohibullah Kakar,

  Roles Resources, Validation

  Affiliation Faculty of Marine Sciences Lasbela University of Agriculture Water and Marine sciences (LUAWMS), Uthal, Balochistan, Pakistan

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• Shabbir Ahmed ,

  Roles Methodology, Software

  * E-mail: shabbirch983@gmail.com (SA); yasmeenshakir@hotmail.com (YS)

  Affiliation Faculty of Animal Husbandry and Veterinary Science, Sindh Agriculture University, Tandojam, Pakistan

  https://orcid.org/0009-0000-3240-7479

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• Hussah M. Alobaid,

  Roles Resources, Visualization, Writing – review & editing

  Affiliation Zoology Department, College of Science, King Saud University, Riyadh, Saudi Arabia

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• Yasmeen Shakir

  Roles Resources, Supervision, Writing – review & editing

  * E-mail: shabbirch983@gmail.com (SA); yasmeenshakir@hotmail.com (YS)

  Affiliation Department of Biochemistry, Hazara University, Mansehra, Khyber Pakhtunkhwa, Pakistan

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