Integrated pan-cancer analysis revealed therapeutic targets in the ABC transporter protein family

Madahiah Bint E Masood; Iqra Shafique; Muhammad Inam Rafique; Ayesha Iman; Ariba Abbasi; Mehak Rafiq; Uzma Habib

doi:10.1371/journal.pone.0308585

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Open Access

Peer-reviewed

Research Article

Integrated pan-cancer analysis revealed therapeutic targets in the ABC transporter protein family

Madahiah Bint E Masood,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation School of Interdisciplinary Engineering & Sciences (SINES), National University of Sciences & Technology, Islamabad, Pakistan

https://orcid.org/0009-0004-5091-6524

⨯
Iqra Shafique,

Roles Formal analysis, Investigation, Software, Validation

Affiliation Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Sciences & Technology, Islamabad, Pakistan
⨯
Muhammad Inam Rafique,

Roles Data curation, Validation, Writing – review & editing

Affiliation School of Interdisciplinary Engineering & Sciences (SINES), National University of Sciences & Technology, Islamabad, Pakistan

https://orcid.org/0009-0009-5825-1201

⨯
Ayesha Iman,

Roles Software, Visualization, Writing – review & editing

Affiliation School of Interdisciplinary Engineering & Sciences (SINES), National University of Sciences & Technology, Islamabad, Pakistan
⨯
Ariba Abbasi,

Roles Data curation, Visualization, Writing – review & editing

Affiliation School of Interdisciplinary Engineering & Sciences (SINES), National University of Sciences & Technology, Islamabad, Pakistan
⨯
Mehak Rafiq ,

Roles Conceptualization, Investigation, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: mehak@sines.nust.edu.pk (MR); uzma.habib@sines.nust.edu.pk (UH)

Affiliation School of Interdisciplinary Engineering & Sciences (SINES), National University of Sciences & Technology, Islamabad, Pakistan

https://orcid.org/0000-0003-1084-6782

⨯
Uzma Habib

Roles Writing – review & editing

* E-mail: mehak@sines.nust.edu.pk (MR); uzma.habib@sines.nust.edu.pk (UH)

Affiliation School of Interdisciplinary Engineering & Sciences (SINES), National University of Sciences & Technology, Islamabad, Pakistan

https://orcid.org/0000-0001-6592-6419

⨯

Integrated pan-cancer analysis revealed therapeutic targets in the ABC transporter protein family

Madahiah Bint E Masood,
Iqra Shafique,
Muhammad Inam Rafique,
Ayesha Iman,
Ariba Abbasi,
Mehak Rafiq,
Uzma Habib

Published: May 30, 2025
https://doi.org/10.1371/journal.pone.0308585

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