Therapeutic potential of archaeal unfoldase PAN^et and the gateless T20S proteasome in P23H rhodopsin retinitis pigmentosa mice

• Celine Brooks ,

  Contributed equally to this work with: Celine Brooks, Douglas Kolson

  Roles Investigation, Writing – original draft, Writing – review & editing

  Affiliations Department of Ophthalmology, West Virginia University, Morgantown, West Virginia, United States of America, Department of Biochemistry and Molecular Medicine, West Virginia University, Morgantown, West Virginia, United States of America

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• Douglas Kolson ,

  Contributed equally to this work with: Celine Brooks, Douglas Kolson

  Roles Conceptualization, Investigation, Writing – original draft

  Affiliation Department of Ophthalmology, West Virginia University, Morgantown, West Virginia, United States of America

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• Emily Sechrest,

  Roles Investigation

  Affiliation Department of Ophthalmology, West Virginia University, Morgantown, West Virginia, United States of America

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• Janelle Chuah,

  Roles Resources

  Affiliation Department of Biochemistry and Molecular Medicine, West Virginia University, Morgantown, West Virginia, United States of America

  https://orcid.org/0000-0002-1139-694X

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• Jane Schupp,

  Roles Investigation

  Affiliation Department of Biochemistry and Molecular Medicine, West Virginia University, Morgantown, West Virginia, United States of America

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• Neil Billington,

  Roles Investigation

  Affiliation Department of Biochemistry and Molecular Medicine, West Virginia University, Morgantown, West Virginia, United States of America

  https://orcid.org/0000-0003-2306-0228

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• Wen-Tao Deng,

  Roles Conceptualization, Investigation, Methodology, Resources

  Affiliations Department of Ophthalmology, West Virginia University, Morgantown, West Virginia, United States of America, Department of Biochemistry and Molecular Medicine, West Virginia University, Morgantown, West Virginia, United States of America

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• David Smith,

  Roles Conceptualization, Investigation, Resources, Supervision, Writing – review & editing

  Affiliations Department of Biochemistry and Molecular Medicine, West Virginia University, Morgantown, West Virginia, United States of America, Department of Neuroscience, West Virginia University, Morgantown, West Virginia, United States of America

  https://orcid.org/0000-0002-1502-676X

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• Maxim Sokolov

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Writing – original draft

  * E-mail: msokolov@hsc.wvu.edu

  Affiliations Department of Ophthalmology, West Virginia University, Morgantown, West Virginia, United States of America, Department of Biochemistry and Molecular Medicine, West Virginia University, Morgantown, West Virginia, United States of America, Department of Neuroscience, West Virginia University, Morgantown, West Virginia, United States of America

  https://orcid.org/0000-0001-5048-8874

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