Causal association of menstrual reproductive factors on the risk of osteoarthritis: A univariate and multivariate Mendelian randomization study

Xinzhe Tan; Yifang Mei; Yihao Zhou; Zhichao Liao; Pengqi Zhang; Yichang Liu; Yixiao Han; Dongyan Wang

doi:10.1371/journal.pone.0307958

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Open Access

Peer-reviewed

Research Article

Causal association of menstrual reproductive factors on the risk of osteoarthritis: A univariate and multivariate Mendelian randomization study

Xinzhe Tan,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Writing – original draft

Affiliation College of Acu-moxibustion and Massage, Heilongjiang University Of Chinese Medicine, Haerbin, Heilongjiang Province, China

https://orcid.org/0009-0001-3738-6176

⨯
Yifang Mei,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Department of Rheumatology and Immunology, The Third People’s Hospital of Shenzhen, Shenzhen, Guangdong Province, China
⨯
Yihao Zhou,

Roles Data curation

Affiliation College of Acu-moxibustion and Massage, Heilongjiang University Of Chinese Medicine, Haerbin, Heilongjiang Province, China
⨯
Zhichao Liao,

Roles Data curation, Software

Affiliation College of Acu-moxibustion and Massage, Heilongjiang University Of Chinese Medicine, Haerbin, Heilongjiang Province, China
⨯
Pengqi Zhang,

Roles Formal analysis, Investigation

Affiliation College of Acu-moxibustion and Massage, Heilongjiang University Of Chinese Medicine, Haerbin, Heilongjiang Province, China
⨯
Yichang Liu,

Roles Investigation

Affiliation College of Acu-moxibustion and Massage, Heilongjiang University Of Chinese Medicine, Haerbin, Heilongjiang Province, China
⨯
Yixiao Han,

Roles Validation

Affiliation College of Acu-moxibustion and Massage, Heilongjiang University Of Chinese Medicine, Haerbin, Heilongjiang Province, China
⨯
Dongyan Wang

Roles Conceptualization, Supervision, Writing – review & editing

* E-mail: doctwdy@163.com

Affiliation Department of Acupuncture and Moxibustion, Heilongjiang University of Chinese Medicine Affiliated Second Hospital, Haerbin, Heilongjiang Province, China
⨯

Causal association of menstrual reproductive factors on the risk of osteoarthritis: A univariate and multivariate Mendelian randomization study

Xinzhe Tan,
Yifang Mei,
Yihao Zhou,
Zhichao Liao,
Pengqi Zhang,
Yichang Liu,
Yixiao Han,
Dongyan Wang

Published: August 30, 2024
https://doi.org/10.1371/journal.pone.0307958

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