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Rationale and protocol for a safety, tolerability and feasibility randomized, parallel arm, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms
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Brianna J. Stubbs ,
Roles Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: bstubbs@buckinstitute.org (BJS); jnewman@buckinstitute.org (JCN)
Affiliation Buck Institute for Research on Aging, Novato, California, United States of America
⨯ - Gabriela Alvarez Azañedo,
- Sawyer Peralta,
- Stephanie Roa Diaz,
- Wyatt Gray,
- Laura Alexander,
- Wendie Silverman-Martin,
- Thelma Y. Garcia,
- Traci M. Blonquist,
- Vaibhav Upadhyay,
- Peter J. Turnbaugh,
- James B. Johnson,
- John C. Newman
https://orcid.org/0000-0001-9566-9134
Rationale and protocol for a safety, tolerability and feasibility randomized, parallel arm, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms
- Brianna J. Stubbs,
- Gabriela Alvarez Azañedo,
- Sawyer Peralta,
- Stephanie Roa Diaz,
- Wyatt Gray,
- Laura Alexander,
- Wendie Silverman-Martin,
- Thelma Y. Garcia,
- Traci M. Blonquist,
- Vaibhav Upadhyay
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- Published: September 18, 2024
- https://doi.org/10.1371/journal.pone.0307951