Development of innovative multi-epitope mRNA vaccine against central nervous system tuberculosis using in silico approaches

Huidong Shi; Yuejie Zhu; Kaiyu Shang; Tingting Tian; Zhengwei Yin; Juan Shi; Yueyue He; Jianbing Ding; Quan Wang; Fengbo Zhang

doi:10.1371/journal.pone.0307877

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Open Access

Peer-reviewed

Research Article

Development of innovative multi-epitope mRNA vaccine against central nervous system tuberculosis using in silico approaches

Huidong Shi,

Roles Data curation, Software, Validation, Writing – original draft

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
⨯
Yuejie Zhu,

Roles Software, Visualization

Affiliation Reproductive Medicine Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
⨯
Kaiyu Shang,

Roles Software, Visualization

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
⨯
Tingting Tian,

Roles Software, Visualization

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
⨯
Zhengwei Yin,

Roles Software, Visualization

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
⨯
Juan Shi,

Roles Software, Visualization

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
⨯
Yueyue He,

Roles Software, Visualization

Affiliation Department of Immunology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, China
⨯
Jianbing Ding,

Roles Software, Visualization

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
⨯
Quan Wang ,

Roles Writing – review & editing

* E-mail: 3197606@qq.com (QW); fengbozhang@xjmu.edu.cn (FZ)

Affiliation Department of Clinical Laboratory, The Eighth Affiliated Hospital of Xinjiang Medical University, Urumqi, China
⨯
Fengbo Zhang

Roles Writing – review & editing

* E-mail: 3197606@qq.com (QW); fengbozhang@xjmu.edu.cn (FZ)

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China

https://orcid.org/0000-0001-5795-8672

⨯

Development of innovative multi-epitope mRNA vaccine against central nervous system tuberculosis using in silico approaches

Huidong Shi,
Yuejie Zhu,
Kaiyu Shang,
Tingting Tian,
Zhengwei Yin,
Juan Shi,
Yueyue He,
Jianbing Ding,
Quan Wang,
Fengbo Zhang

Published: September 6, 2024
https://doi.org/10.1371/journal.pone.0307877

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