Evaluation of ex vivo drug combination optimization platform in recurrent high grade astrocytic glioma: An interventional, non-randomized, open-label trial protocol

• Tan Boon Toh ,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: lsittb@nus.edu.sg (TBT); Andrea_LA_WONG@nuhs.edu.sg (ALAW)

  Affiliations The N.1 Institute for Health (N.1), National University of Singapore, Singapore, Singapore, The Institute for Digital Medicine (WisDM), National University of Singapore, Singapore, Singapore

  https://orcid.org/0000-0003-0292-6985

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• Dexter Kai Hao Thng,

  Roles Writing – review & editing

  Affiliations The N.1 Institute for Health (N.1), National University of Singapore, Singapore, Singapore, Cancer Science Institute of Singapore (CSI), National University of Singapore, Singapore, Singapore

  https://orcid.org/0000-0002-1325-4347

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• Nagarjun Bolem,

  Roles Investigation, Writing – original draft

  Affiliation Division of Neurosurgery, Department of Surgery, National University Hospital, Singapore, Singapore

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• Balamurugan A. Vellayappan,

  Roles Conceptualization, Investigation

  Affiliation Department of Radiation Oncology, National University Cancer Institute, Singapore, Singapore

  ⨯
• Bryce Wei Quan Tan,

  Roles Investigation, Writing – original draft

  Affiliation Cancer Science Institute of Singapore (CSI), National University of Singapore, Singapore, Singapore

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• Yating Shen,

  Roles Investigation

  Affiliations The N.1 Institute for Health (N.1), National University of Singapore, Singapore, Singapore, Cancer Science Institute of Singapore (CSI), National University of Singapore, Singapore, Singapore

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• Sou Yen Soon,

  Roles Project administration, Writing – original draft

  Affiliation Department of Haematology-Oncology, National University Hospital, Singapore, Singapore

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• Yvonne Li En Ang,

  Roles Investigation

  Affiliation Department of Haematology-Oncology, National University Hospital, Singapore, Singapore

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• Nivedh Dinesh,

  Roles Investigation

  Affiliation Division of Neurosurgery, Department of Surgery, National University Hospital, Singapore, Singapore

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• Kejia Teo,

  Roles Investigation

  Affiliation Division of Neurosurgery, Department of Surgery, National University Hospital, Singapore, Singapore

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• Vincent Diong Weng Nga,

  Roles Investigation

  Affiliation Division of Neurosurgery, Department of Surgery, National University Hospital, Singapore, Singapore

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• Shiong Wen Low,

  Roles Investigation

  Affiliation Division of Neurological Surgery, Ng Teng Fong General Hospital, Singapore, Singapore

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• Pek Lan Khong,

  Roles Investigation, Writing – original draft

  Affiliations Department of Diagnostic Imaging, National University Hospital, Singapore, Singapore, Clinical Imaging Research Centre (CIRC), National University of Singapore, Singapore, Singapore

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• Edward Kai-Hua Chow,

  Roles Conceptualization, Investigation, Software

  Affiliations The N.1 Institute for Health (N.1), National University of Singapore, Singapore, Singapore, The Institute for Digital Medicine (WisDM), National University of Singapore, Singapore, Singapore, Cancer Science Institute of Singapore (CSI), National University of Singapore, Singapore, Singapore

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• Dean Ho,

  Roles Conceptualization, Funding acquisition, Investigation, Software

  Affiliations The N.1 Institute for Health (N.1), National University of Singapore, Singapore, Singapore, The Institute for Digital Medicine (WisDM), National University of Singapore, Singapore, Singapore

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• Tseng Tsai Yeo,

  Roles Conceptualization, Funding acquisition, Investigation

  Affiliation Division of Neurosurgery, Department of Surgery, National University Hospital, Singapore, Singapore

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•  [ ... ],
• Andrea Li Ann Wong

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: lsittb@nus.edu.sg (TBT); Andrea_LA_WONG@nuhs.edu.sg (ALAW)

  Affiliations Cancer Science Institute of Singapore (CSI), National University of Singapore, Singapore, Singapore, Department of Haematology-Oncology, National University Hospital, Singapore, Singapore

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