Vitamin K2 sensitizes the efficacy of venetoclax in acute myeloid leukemia by targeting the NOXA-MCL-1 pathway

• Tetsuzo Tauchi ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: tauchi144@gmail.com (TT); ntakano@tokyo-med.ac.jp (NT)

  Affiliation Shinyurigaoka General Hospital, Asou-ku, Kawasaki, Kanagawa, Japan

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• Shota Moriya,

  Roles Data curation, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan

  https://orcid.org/0000-0002-9921-2622

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• Seiichi Okabe,

  Roles Data curation, Investigation, Methodology, Validation

  Affiliation Department of Hematology, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan

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• Hiromi Kazama,

  Roles Data curation, Investigation, Validation, Visualization

  Affiliation Department of Biochemistry, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan

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• Keisuke Miyazawa,

  Roles Conceptualization, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan

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• Naoharu Takano

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: tauchi144@gmail.com (TT); ntakano@tokyo-med.ac.jp (NT)

  Affiliation Department of Biochemistry, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan

  https://orcid.org/0000-0003-3364-2731

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