Targeting prostate cancer by new bispecific monocyte engager directed to prostate-specific membrane antigen

Gargi Das; Jakub Ptacek; Jana Campbell; Xintang Li; Barbora Havlinova; Satish kumar Noonepalle; Alejandro Villagra; Cyril Barinka; Zora Novakova

doi:10.1371/journal.pone.0307353

Loading metrics

Open Access

Peer-reviewed

Research Article

Targeting prostate cancer by new bispecific monocyte engager directed to prostate-specific membrane antigen

Gargi Das,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft

Affiliations Laboratory of Structural Biology, Institute of Biotechnology of the Czech Academy of Sciences, Vestec, Czech Republic, Department of Cell Biology, Faculty of Science, Charles University, Prague, Czech Republic
⨯
Jakub Ptacek,

Roles Conceptualization, Investigation, Writing – original draft

Affiliation Laboratory of Structural Biology, Institute of Biotechnology of the Czech Academy of Sciences, Vestec, Czech Republic
⨯
Jana Campbell,

Roles Formal analysis, Investigation

Affiliation Laboratory of Structural Biology, Institute of Biotechnology of the Czech Academy of Sciences, Vestec, Czech Republic
⨯
Xintang Li,

Roles Formal analysis, Investigation, Writing – original draft

Affiliation Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D.C., United States of America
⨯
Barbora Havlinova,

Roles Investigation

Affiliation Laboratory of Structural Biology, Institute of Biotechnology of the Czech Academy of Sciences, Vestec, Czech Republic
⨯
Satish kumar Noonepalle,

Roles Formal analysis, Investigation, Methodology

Affiliation Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D.C., United States of America
⨯
Alejandro Villagra,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliation Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D.C., United States of America

https://orcid.org/0000-0001-9346-8355

⨯
Cyril Barinka,

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft

Affiliation Laboratory of Structural Biology, Institute of Biotechnology of the Czech Academy of Sciences, Vestec, Czech Republic
⨯
Zora Novakova

Roles Conceptualization, Investigation, Supervision, Writing – original draft

* E-mail: zora.novakova@ibt.cas.cz

Affiliation Laboratory of Structural Biology, Institute of Biotechnology of the Czech Academy of Sciences, Vestec, Czech Republic

https://orcid.org/0000-0001-9804-6346

⨯

Targeting prostate cancer by new bispecific monocyte engager directed to prostate-specific membrane antigen

Gargi Das,
Jakub Ptacek,
Jana Campbell,
Xintang Li,
Barbora Havlinova,
Satish kumar Noonepalle,
Alejandro Villagra,
Cyril Barinka,
Zora Novakova

Published: March 17, 2025
https://doi.org/10.1371/journal.pone.0307353

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Prostate cancer
Is the Subject Area "Prostate cancer" applicable to this article?

Thanks for your feedback.
Monocytes
Is the Subject Area "Monocytes" applicable to this article?

Thanks for your feedback.
Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Phagocytosis
Is the Subject Area "Phagocytosis" applicable to this article?

Thanks for your feedback.
Cancer immunotherapy
Is the Subject Area "Cancer immunotherapy" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Cell fusion
Is the Subject Area "Cell fusion" applicable to this article?

Thanks for your feedback.
Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.