Integration of the PD-L1 inhibitor atezolizumab and WT1/DC vaccination into standard-of-care first-line treatment for patients with epithelioid malignant pleural mesothelioma—Protocol of the Immuno-MESODEC study

• Jolien Van den Bossche ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Writing – original draft

  ¶‡ JVB, MDL, KD and PG share first authorship on this work. SA, EL and ZB are joint senior authors on this work.

  Affiliation Center for Cell Therapy and Regenerative Medicine (CCRG), Antwerp University Hospital (UZA), Edegem, Belgium

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• Maxime De Laere ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Visualization, Writing – original draft

  * E-mail: Maxime.DeLaere@uza.be

  ¶‡ JVB, MDL, KD and PG share first authorship on this work. SA, EL and ZB are joint senior authors on this work.

  Affiliations Center for Cell Therapy and Regenerative Medicine (CCRG), Antwerp University Hospital (UZA), Edegem, Belgium, Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium

  https://orcid.org/0000-0002-1434-0837

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• Koen Deschepper ,

  Roles Conceptualization, Investigation, Methodology, Resources, Writing – review & editing

  ¶‡ JVB, MDL, KD and PG share first authorship on this work. SA, EL and ZB are joint senior authors on this work.

  Affiliation Division of Pulmonary and Infectious Diseases, VITAZ, Sint-Niklaas, Belgium

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• Paul Germonpré ,

  Roles Conceptualization, Investigation, Methodology, Resources, Writing – review & editing

  ¶‡ JVB, MDL, KD and PG share first authorship on this work. SA, EL and ZB are joint senior authors on this work.

  Affiliation Respiratory Oncology & Integrated Cancer Cancer Ghent, AZ Maria Middelares, Ghent, Belgium

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• Yvan Valcke,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Division of Pulmonary and Infectious Diseases, VITAZ, Sint-Niklaas, Belgium

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• Jan Lamont,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Respiratory Oncology & Integrated Cancer Cancer Ghent, AZ Maria Middelares, Ghent, Belgium

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• Barbara Stein,

  Roles Conceptualization, Methodology, Project administration, Writing – review & editing

  Affiliation Center for Cell Therapy and Regenerative Medicine (CCRG), Antwerp University Hospital (UZA), Edegem, Belgium

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• Kirsten Van Camp,

  Roles Investigation, Project administration, Writing – review & editing

  Affiliation Division of Pulmonary and Infectious Diseases, VITAZ, Sint-Niklaas, Belgium

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• Charlotte Germonpré,

  Roles Investigation, Project administration, Writing – review & editing

  Affiliation Respiratory Oncology & Integrated Cancer Cancer Ghent, AZ Maria Middelares, Ghent, Belgium

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• Griet Nijs,

  Roles Project administration, Resources, Writing – review & editing

  Affiliation Center for Cell Therapy and Regenerative Medicine (CCRG), Antwerp University Hospital (UZA), Edegem, Belgium

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• Ella Roelant,

  Roles Methodology, Software, Writing – review & editing

  Affiliation Clinical Trial Center (CTC), CRC Antwerp, Antwerp University Hospital (UZA), University of Antwerp, Edegem, Belgium

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• Sébastien Anguille ,

  Roles Funding acquisition, Resources, Writing – review & editing

  ¶‡ JVB, MDL, KD and PG share first authorship on this work. SA, EL and ZB are joint senior authors on this work.

  Affiliations Center for Cell Therapy and Regenerative Medicine (CCRG), Antwerp University Hospital (UZA), Edegem, Belgium, Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium, Division of Hematology, Antwerp University Hospital (UZA), Edegem, Belgium

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• Eva Lion ,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

  ¶‡ JVB, MDL, KD and PG share first authorship on this work. SA, EL and ZB are joint senior authors on this work.

  Affiliations Center for Cell Therapy and Regenerative Medicine (CCRG), Antwerp University Hospital (UZA), Edegem, Belgium, Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium

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• Zwi Berneman

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  ¶‡ JVB, MDL, KD and PG share first authorship on this work. SA, EL and ZB are joint senior authors on this work.

  Affiliations Center for Cell Therapy and Regenerative Medicine (CCRG), Antwerp University Hospital (UZA), Edegem, Belgium, Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium, Division of Hematology, Antwerp University Hospital (UZA), Edegem, Belgium

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