Explainable machine learning on baseline MRI predicts multiple sclerosis trajectory descriptors

• Silvia Campanioni,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Galicia Sur Health Research Institute (IIS Galicia Sur), Cardiovascular Research Group, Vigo, Spain

  https://orcid.org/0000-0002-9088-1336

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• César Veiga ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: cesar.veiga@iisgaliciasur.es (CV); josemaoscar.prieto@usc.es (JMPG)

  Affiliation Galicia Sur Health Research Institute (IIS Galicia Sur), Cardiovascular Research Group, Vigo, Spain

  https://orcid.org/0000-0003-4165-5049

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• José María Prieto-González ,

  Roles Conceptualization, Formal analysis, Investigation, Supervision, Writing – review & editing

  * E-mail: cesar.veiga@iisgaliciasur.es (CV); josemaoscar.prieto@usc.es (JMPG)

  Affiliations Health Research Institute of Santiago de Compostela (IDIS), Translational Research in Neurological Diseases Group, Santiago University Hospital Complex, SERGAS-USC, Santiago de Compostela, Spain, Neuro Epigenetics Lab, Health Research Institute of Santiago de Compostela (IDIS), Santiago University Hospital Complex, Santiago de Compostela, Spain, Neurology Service, Santiago University Hospital Complex, Santiago de Compostela, Spain

  https://orcid.org/0000-0002-8170-0724

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• José A. González-Nóvoa,

  Roles Investigation, Methodology, Software, Validation, Writing – review & editing

  Affiliation Galicia Sur Health Research Institute (IIS Galicia Sur), Cardiovascular Research Group, Vigo, Spain

  https://orcid.org/0000-0003-2334-1556

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• Laura Busto,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Galicia Sur Health Research Institute (IIS Galicia Sur), Cardiovascular Research Group, Vigo, Spain

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• Carlos Martinez,

  Roles Investigation, Writing – review & editing

  Affiliation Galicia Sur Health Research Institute (IIS Galicia Sur), Cardiovascular Research Group, Vigo, Spain

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• Miguel Alberte-Woodward,

  Roles Investigation, Supervision, Writing – review & editing

  Affiliations Health Research Institute of Santiago de Compostela (IDIS), Translational Research in Neurological Diseases Group, Santiago University Hospital Complex, SERGAS-USC, Santiago de Compostela, Spain, Neuro Epigenetics Lab, Health Research Institute of Santiago de Compostela (IDIS), Santiago University Hospital Complex, Santiago de Compostela, Spain, Neurology Service, Santiago University Hospital Complex, Santiago de Compostela, Spain

  https://orcid.org/0000-0002-7537-8740

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• Jesús García de Soto,

  Roles Investigation, Writing – review & editing

  Affiliations Health Research Institute of Santiago de Compostela (IDIS), Translational Research in Neurological Diseases Group, Santiago University Hospital Complex, SERGAS-USC, Santiago de Compostela, Spain, Neuro Epigenetics Lab, Health Research Institute of Santiago de Compostela (IDIS), Santiago University Hospital Complex, Santiago de Compostela, Spain, Neurology Service, Santiago University Hospital Complex, Santiago de Compostela, Spain

  https://orcid.org/0000-0003-1774-4922

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• Jessica Pouso-Diz,

  Roles Investigation, Writing – review & editing

  Affiliations Health Research Institute of Santiago de Compostela (IDIS), Translational Research in Neurological Diseases Group, Santiago University Hospital Complex, SERGAS-USC, Santiago de Compostela, Spain, Neuro Epigenetics Lab, Health Research Institute of Santiago de Compostela (IDIS), Santiago University Hospital Complex, Santiago de Compostela, Spain, Neurology Service, Santiago University Hospital Complex, Santiago de Compostela, Spain

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• María de los Ángeles Fernández Ceballos,

  Roles Investigation, Writing – review & editing

  Affiliations Health Research Institute of Santiago de Compostela (IDIS), Translational Research in Neurological Diseases Group, Santiago University Hospital Complex, SERGAS-USC, Santiago de Compostela, Spain, Neuro Epigenetics Lab, Health Research Institute of Santiago de Compostela (IDIS), Santiago University Hospital Complex, Santiago de Compostela, Spain, Neurology Service, Santiago University Hospital Complex, Santiago de Compostela, Spain

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• Roberto Carlos Agis-Balboa

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliations Health Research Institute of Santiago de Compostela (IDIS), Translational Research in Neurological Diseases Group, Santiago University Hospital Complex, SERGAS-USC, Santiago de Compostela, Spain, Neuro Epigenetics Lab, Health Research Institute of Santiago de Compostela (IDIS), Santiago University Hospital Complex, Santiago de Compostela, Spain, Neurology Service, Santiago University Hospital Complex, Santiago de Compostela, Spain

  https://orcid.org/0000-0001-9899-9569

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