The polygenic implication of clopidogrel responsiveness: Insights from platelet reactivity analysis and next-generation sequencing

• Omar Echeverría ,

  Contributed equally to this work with: Omar Echeverría, Mariana Angulo-Aguado

  Roles Data curation, Formal analysis, Investigation, Software, Writing – original draft

  Affiliation School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia

  https://orcid.org/0009-0000-6753-0178

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• Mariana Angulo-Aguado ,

  Contributed equally to this work with: Omar Echeverría, Mariana Angulo-Aguado

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia

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• Ricardo Vela,

  Roles Formal analysis, Investigation, Software

  Affiliation School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia

  ⨯
• Carlos Calderón-Ospina,

  Roles Conceptualization, Data curation, Formal analysis, Writing – review & editing

  Affiliation School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia

  ⨯
• Katherine Parra,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Hospital Universitario Mayor—Méderi—Universidad del Rosario, Bogotá D.C., Colombia

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• Nora Contreras,

  Roles Data curation, Formal analysis, Methodology

  Affiliation School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia

  ⨯
• Adrien Morel,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia

  ⨯
• Rodrigo Cabrera,

  Roles Investigation, Methodology, Software, Validation

  Affiliation School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia

  ⨯
• Carlos Restrepo,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia

  https://orcid.org/0000-0001-6410-0084

  ⨯
• Carolina Ramírez-Santana,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Bogotá D.C., Colombia

  ⨯
• Oscar Ortega-Recalde,

  Roles Formal analysis, Methodology, Software, Validation, Writing – review & editing

  Affiliations School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia, Departamento de Morfología, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá D.C., Colombia

  ⨯
• Manuel Eduardo Rojas-Quintana,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – review & editing

  Affiliations Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Bogotá D.C., Colombia, Division of Rheumatology, Allergy and Clinical Immunology, University of California, Davis, CA, United States of America

  https://orcid.org/0000-0002-8604-4658

  ⨯
• Luisa Murcia,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation Hospital Universitario Mayor—Méderi—Universidad del Rosario, Bogotá D.C., Colombia

  https://orcid.org/0000-0003-2998-8561

  ⨯
• Cristian Camilo Gaviria-Sabogal,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – review & editing

  Affiliation School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia

  https://orcid.org/0009-0004-9482-4373

  ⨯
• Nattaly Valero,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – review & editing

  Affiliation School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia

  ⨯
•  [ ... ],
• Dora Janeth Fonseca-Mendoza

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – review & editing

  * E-mail: dora.fonseca@urosario.edu.co

  Affiliation School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia

  https://orcid.org/0000-0002-7323-6570

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