Beyond its preferential niche: Brucella abortus RNA down-modulates the IFN-γ-induced MHC-I expression in epithelial and endothelial cells

Agustina Serafino; Yasmín A. Bertinat; Jorgelina Bueno; José R. Pittaluga; Federico Birnberg Weiss; M. Ayelén Milillo; Paula Barrionuevo

doi:10.1371/journal.pone.0306429

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Peer-reviewed

Research Article

Beyond its preferential niche: Brucella abortus RNA down-modulates the IFN-γ-induced MHC-I expression in epithelial and endothelial cells

Agustina Serafino,

Roles Investigation, Methodology, Visualization, Writing – original draft

Affiliation Instituto de Medicina Experimental-Consejo Nacional de Investigaciones Científicas y Técnicas, Academia Nacional de Medicina; Buenos Aires, Argentina
⨯
Yasmín A. Bertinat,

Roles Investigation, Methodology

Affiliation Instituto de Medicina Experimental-Consejo Nacional de Investigaciones Científicas y Técnicas, Academia Nacional de Medicina; Buenos Aires, Argentina
⨯
Jorgelina Bueno,

Roles Investigation

Affiliation Instituto de Medicina Experimental-Consejo Nacional de Investigaciones Científicas y Técnicas, Academia Nacional de Medicina; Buenos Aires, Argentina
⨯
José R. Pittaluga,

Roles Investigation, Methodology

Affiliation Instituto de Medicina Experimental-Consejo Nacional de Investigaciones Científicas y Técnicas, Academia Nacional de Medicina; Buenos Aires, Argentina
⨯
Federico Birnberg Weiss,

Roles Investigation

Affiliation Instituto de Medicina Experimental-Consejo Nacional de Investigaciones Científicas y Técnicas, Academia Nacional de Medicina; Buenos Aires, Argentina
⨯
M. Ayelén Milillo ,

Contributed equally to this work with: M. Ayelén Milillo, Paula Barrionuevo

Roles Formal analysis, Investigation, Resources, Supervision, Writing – review & editing

* E-mail: mililloayelen@gmail.com

Affiliations Universidad Nacional de Río Negro. Instituto de Estudios en Ciencia, Tecnología, Cultura y Desarrollo. Río Negro, Argentina, Consejo Nacional de Investigaciones Científicas y Técnicas. Argentina

https://orcid.org/0000-0002-7891-5169

⨯
Paula Barrionuevo

Contributed equally to this work with: M. Ayelén Milillo, Paula Barrionuevo

Roles Formal analysis, Resources, Writing – original draft, Writing – review & editing

Affiliation Instituto de Medicina Experimental-Consejo Nacional de Investigaciones Científicas y Técnicas, Academia Nacional de Medicina; Buenos Aires, Argentina
⨯

Beyond its preferential niche: Brucella abortus RNA down-modulates the IFN-γ-induced MHC-I expression in epithelial and endothelial cells

Agustina Serafino,
Yasmín A. Bertinat,
Jorgelina Bueno,
José R. Pittaluga,
Federico Birnberg Weiss,
M. Ayelén Milillo,
Paula Barrionuevo

Published: July 9, 2024
https://doi.org/10.1371/journal.pone.0306429

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Respiratory infections
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Flow cytometry
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Brucellosis
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Epithelium
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Endothelial cells
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Brucella
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