An international study to investigate and optimise the safety of discontinuing valproate in young men and women with epilepsy: Protocol

• Gashirai K. Mbizvo ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: Gashirai.Mbizvo@liverpool.ac.uk

  Affiliations Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom, Institute of Systems, Molecular and Integrative Biology, Pharmacology and Therapeutics, University of Liverpool, Liverpool, United Kingdom, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom

  https://orcid.org/0000-0002-9588-2944

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• Glen P. Martin,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Faculty of Biology, Division of Informatics, Imaging and Data Science, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

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• Matthew Sperrin,

  Roles Conceptualization, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Faculty of Biology, Division of Informatics, Imaging and Data Science, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

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• Laura J. Bonnett,

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  Affiliation University of Liverpool Department of Biostatistics, Liverpool, United Kingdom

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• Pieta Schofield,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Public Health, Policy and Systems, Institute of Population Health, University of Liverpool, Liverpool, United Kingdom

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• Iain Buchan,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Public Health, Policy and Systems, Institute of Population Health, University of Liverpool, Liverpool, United Kingdom

  https://orcid.org/0000-0003-3392-1650

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• Gregory Y. H. Lip ,

  Roles Conceptualization, Supervision, Writing – review & editing

  ¶‡ GYHL and AGM are Joint senior authors.

  Affiliations Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom, Department of Clinical Medicine, Danish Centre for Health Services Research, Aalborg University, Aalborg, Denmark

  https://orcid.org/0000-0002-7566-1626

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• Anthony G. Marson

  Roles Conceptualization, Supervision, Writing – review & editing

  ¶‡ GYHL and AGM are Joint senior authors.

  Affiliations Institute of Systems, Molecular and Integrative Biology, Pharmacology and Therapeutics, University of Liverpool, Liverpool, United Kingdom, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom

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