A machine-learning based model for automated recommendation of individualized treatment of rifampicin-resistant tuberculosis

• Lennert Verboven ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: lennert.verboven@uantwerpen.be, lennert.verboven@protonmail.com

  Affiliations Torch Consortium FAMPOP Faculty of Medicine and Health Sciences, University of Antwerp, Antwerpen, Belgium, Department of Computer Science, ADReM Data Lab, University of Antwerp, Antwerpen, Belgium

  https://orcid.org/0000-0002-5647-5852

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• Steven Callens,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Internal Medicine & Infectious diseases, Ghent University Hospital, Ghent, Belgium

  https://orcid.org/0000-0002-7245-527X

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• John Black,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Internal Medicine, University of Cape Town and Livingstone Hospital, Port Elizabeth, South Africa

  https://orcid.org/0000-0002-7845-4972

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• Gary Maartens,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Medicine, Division of Clinical Pharmacology, University of Cape Town, Cape Town, South Africa

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• Kelly E. Dooley,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America

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• Samantha Potgieter,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Internal Medicine, Division of Infectious Diseases, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa

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• Ruben Cartuyvels,

  Roles Software, Writing – review & editing

  Affiliation Department of Computer Science, KU Leuven, Belgium

  https://orcid.org/0000-0003-1063-4659

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• SMARTT team ,

  ¶Membership of the SMARTT team is provided in the acknowledgements.

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• Kris Laukens,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Computer Science, ADReM Data Lab, University of Antwerp, Antwerpen, Belgium

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• Robin M. Warren,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Writing – review & editing

  Affiliation DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Stellenbosch University, Cape Town, South Africa

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• Annelies Van Rie

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Torch Consortium FAMPOP Faculty of Medicine and Health Sciences, University of Antwerp, Antwerpen, Belgium

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