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Open Access

Peer-reviewed

Research Article

Mutation accumulation in H. sapiens F508del CFTR countermands dN/dS type genomic analysis

Jeong S. Hong,

Roles Formal analysis, Investigation, Validation, Visualization

Affiliation Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Janice M. Tindall,

Roles Data curation, Formal analysis, Investigation

Affiliation Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Samuel R. Tindall,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology

Affiliation Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Eric J. Sorscher

Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: esorscher@emory.edu

Affiliation Emory University School of Medicine, Atlanta, Georgia, United States of America

https://orcid.org/0000-0001-9341-3354

⨯

Mutation accumulation in H. sapiens F508del CFTR countermands dN/dS type genomic analysis

Jeong S. Hong,
Janice M. Tindall,
Samuel R. Tindall,
Eric J. Sorscher

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Published: July 18, 2024
https://doi.org/10.1371/journal.pone.0305832

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Single nucleotide polymorphisms
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Mutation
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Point mutation
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Cystic fibrosis
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Natural selection
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Parallel evolution
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Homozygosity
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Molecular evolution
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