Preclinical studies of RA475, a guanidine-substituted spirocyclic candidate RPN13/ADRM1 inhibitor for treatment of ovarian cancer

• Ravi K. Anchoori,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Oncology, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Ssu-Hsueh Tseng,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Hua-Ling Tsai,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – review & editing

  Affiliation Department of Oncology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Vikrant Palande,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Michelle A. Rudek †,

  † Deceased.

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Oncology, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

  https://orcid.org/0000-0001-5739-6868

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• Richard B. S. Roden

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: roden@jhmi.edu

  Affiliations Department of Oncology, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America

  https://orcid.org/0000-0002-2506-0195

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