Designing target trials using electronic health records: A case study of second-line disease-modifying anti-rheumatic drugs and cardiovascular disease outcomes in patients with rheumatoid arthritis

• Adovich S. Rivera,

  Roles Conceptualization, Formal analysis, Methodology, Visualization, Writing – original draft

  Affiliations Institute for Public Health and Management, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, United States of America

  https://orcid.org/0000-0003-2533-0818

  ⨯
• Jacob B. Pierce,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Medicine, Duke University School of Medicine, Durham, North Carolina, United States of America

  ⨯
• Arjun Sinha,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Medicine, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

  ⨯
• Anna E. Pawlowski,

  Roles Data curation, Writing – review & editing

  Affiliation Northwestern Medicine Enterprise Data Warehouse, Northwestern University, Chicago, Illinois, United States of America

  https://orcid.org/0000-0002-9047-6437

  ⨯
• Donald M. Lloyd-Jones,

  Roles Methodology, Writing – review & editing

  Affiliations Department of Medicine, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Department of Preventive Medicine, Division of Epidemiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

  ⨯
• Yvonne C. Lee,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Medicine, Division of Rheumatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

  ⨯
• Matthew J. Feinstein,

  Roles Conceptualization, Methodology, Resources, Writing – review & editing

  Affiliations Department of Medicine, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Department of Preventive Medicine, Division of Epidemiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

  ⨯
• Lucia C. Petito

  Roles Conceptualization, Formal analysis, Methodology, Supervision, Writing – original draft

  * E-mail: lucia.petito@northwestern.edu

  Affiliation Department of Preventive Medicine, Division of Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

  ⨯