Transmural APD heterogeneity determines ventricular arrhythmogenesis in LQT8 syndrome: Insights from Bidomain computational modeling

• Simone Scacchi,

  Roles Conceptualization, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Dipartimento di Matematica, Università degli Studi di Milano, Milano, Italy

  ⨯
• Luca F. Pavarino ,

  Roles Conceptualization, Methodology, Validation, Writing – original draft, Writing – review & editing

  * E-mail: luca.pavarino@unipv.it

  Affiliation Dipartimento di Matematica, Università degli Studi di Pavia, Pavia, Italy

  https://orcid.org/0000-0002-3014-4668

  ⨯
• Andrea Mazzanti,

  Roles Methodology, Validation, Writing – review & editing

  Affiliations Molecular Cardiology, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain, Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy, Department of Molecular Medicine, University of Pavia, Pavia, Italy

  ⨯
• Alessandro Trancuccio,

  Roles Methodology, Validation, Writing – review & editing

  Affiliations Molecular Cardiology, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain, Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy, Department of Molecular Medicine, University of Pavia, Pavia, Italy

  ⨯
• Silvia G. Priori,

  Roles Methodology, Validation, Writing – review & editing

  Affiliations Molecular Cardiology, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain, Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy, Department of Molecular Medicine, University of Pavia, Pavia, Italy

  ⨯
• Piero Colli Franzone

  Roles Conceptualization, Methodology, Validation, Writing – original draft

  ¶† Deceased. The Authors dedicate this work to the memory of Piero Colli Franzone.

  Affiliation Dipartimento di Matematica, Università degli Studi di Pavia, Pavia, Italy

  ⨯