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Open Access
Peer-reviewed
Research Article
A metabolic profile of xenon and metabolite associations with 6-month mortality after out-of-hospital cardiac arrest: A post-hoc study of the randomised Xe-Hypotheca trial
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Aleksi J. Nummela ,
Roles Data curation, Funding acquisition, Software, Validation, Visualization, Writing – original draft
* E-mail: aljunu@utu.fi
Affiliation Department of Internal Medicine, Turku University Hospital, University of Turku, Turku, Finland
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Harry Scheinin,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Perioperative Services, Intensive Care and Pain Management, Turku University Hospital, University of Turku, Turku, Finland, Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland
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Markus Perola,
Roles Writing – review & editing
Affiliations Finnish Institute for Health and Welfare, Helsinki, Finland, Faculty of Medicine, Research Program for Clinical and Molecular Metabolism, University of Helsinki, Helsinki, Finland
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Anni Joensuu,
Roles Formal analysis, Writing – review & editing
Affiliations Finnish Institute for Health and Welfare, Helsinki, Finland, Faculty of Medicine, Research Program for Clinical and Molecular Metabolism, University of Helsinki, Helsinki, Finland
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Ruut Laitio,
Roles Investigation, Writing – review & editing
Affiliation Department of Perioperative Services, Intensive Care and Pain Management, Turku University Hospital, University of Turku, Turku, Finland
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Olli Arola,
Roles Investigation, Writing – review & editing
Affiliation Department of Perioperative Services, Intensive Care and Pain Management, Turku University Hospital, University of Turku, Turku, Finland
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Juha Grönlund,
Roles Investigation, Writing – review & editing
Affiliation Department of Perioperative Services, Intensive Care and Pain Management, Turku University Hospital, University of Turku, Turku, Finland
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Risto O. Roine,
Roles Funding acquisition, Writing – review & editing
Affiliation Division of Clinical Neurosciences, University of Turku, Turku University Hospital, Turku, Finland
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Minna Bäcklund,
Roles Investigation, Writing – review & editing
Affiliation Department of Anesthesiology, Intensive Care and Pain Medicine, Division of Intensive Care Medicine, University of Helsinki and HUS Helsinki University Hospital, Helsinki, Finland
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Tero J. Vahlberg,
Roles Formal analysis, Validation, Writing – review & editing
Affiliation Department of Biostatistics, University of Turku and Turku University Hospital, Turku, Finland
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Timo Laitio,
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing
Affiliation Department of Perioperative Services, Intensive Care and Pain Management, Turku University Hospital, University of Turku, Turku, Finland
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for the Xe-Hypotheca Collaboration Group
¶The membership of Xe-Hypotheca Collaboration Group is provided in the Acknowledgments.
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A metabolic profile of xenon and metabolite associations with 6-month mortality after out-of-hospital cardiac arrest: A post-hoc study of the randomised Xe-Hypotheca trial
- Aleksi J. Nummela,
- Harry Scheinin,
- Markus Perola,
- Anni Joensuu,
- Ruut Laitio,
- Olli Arola,
- Juha Grönlund,
- Risto O. Roine,
- Minna Bäcklund,
- Tero J. Vahlberg
- Published: June 4, 2024
- https://doi.org/10.1371/journal.pone.0304966