Enhanced thermal stability enables human mismatch-specific thymine–DNA glycosylase to catalyse futile DNA repair

• Diana Manapkyzy,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliations Department of Molecular Biology and Genetics, Faculty of Biology and Biotechnology, al-Farabi Kazakh National University, Almaty, Kazakhstan, Scientific Research Institute of Biology and Biotechnology Problems, al-Farabi Kazakh National University, Almaty, Kazakhstan

  ⨯
• Botagoz Joldybayeva,

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

  Affiliations Department of Molecular Biology and Genetics, Faculty of Biology and Biotechnology, al-Farabi Kazakh National University, Almaty, Kazakhstan, Scientific Research Institute of Biology and Biotechnology Problems, al-Farabi Kazakh National University, Almaty, Kazakhstan

  ⨯
• Alexander A. Ishchenko,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Validation

  Affiliation Group «Mechanisms of DNA Repair and Carcinogenesis», CNRS UMR9019, Université Paris-Saclay, Gustave Roussy Cancer Campus, Villejuif Cedex, France

  ⨯
• Bakhyt T. Matkarimov,

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Software

  Affiliation National Laboratory Astana, Nazarbayev University, Astana, Kazakhstan

  ⨯
• Dmitry O. Zharkov,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliations SB RAS Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia, Department of Natural Sciences, Novosibirsk State University, Novosibirsk, Russia

  https://orcid.org/0000-0001-5013-0194

  ⨯
• Sabira Taipakova ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: murat.saparbaev@gustaveroussy.fr (MKS); sabira.taipakova@gmail.com (ST)

  Affiliations Department of Molecular Biology and Genetics, Faculty of Biology and Biotechnology, al-Farabi Kazakh National University, Almaty, Kazakhstan, Scientific Research Institute of Biology and Biotechnology Problems, al-Farabi Kazakh National University, Almaty, Kazakhstan, National Laboratory Astana, Nazarbayev University, Astana, Kazakhstan

  https://orcid.org/0000-0001-9499-1682

  ⨯
• Murat K. Saparbaev

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: murat.saparbaev@gustaveroussy.fr (MKS); sabira.taipakova@gmail.com (ST)

  Affiliation Group «Mechanisms of DNA Repair and Carcinogenesis», CNRS UMR9019, Université Paris-Saclay, Gustave Roussy Cancer Campus, Villejuif Cedex, France

  https://orcid.org/0000-0002-4630-1074

  ⨯