Study protocol for ADHERE (Applying Directly observed therapy to HydroxyurEa to Realize Effectiveness): Using small business partnerships to deliver a scalable and novel hydroxyurea adherence solution to youth with sickle cell disease

• Joseph Walden,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Center for Child Health Equity and Outcomes Research, The Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH, United States of America

  https://orcid.org/0000-0002-4111-1845

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• Lauren Brown,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation emocha Mobile Health Inc. Doing Business as Scene and Scene Health, Baltimore, MD, United States of America

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• Sebastian Seiguer,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  Affiliation emocha Mobile Health Inc. Doing Business as Scene and Scene Health, Baltimore, MD, United States of America

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• Katie Munshaw,

  Roles Conceptualization, Investigation, Methodology, Project administration, Resources, Writing – review & editing

  Affiliation emocha Mobile Health Inc. Doing Business as Scene and Scene Health, Baltimore, MD, United States of America

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• Joseph Rausch,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliations Center for Biobehavioral Health, The Research Institute at Nationwide Children’s Hospital, Columbus, OH, United States of America, Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, United States of America

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• Sherif Badawy,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  Affiliations Division of Hematology, Oncology, and Stem Cell Transplant, Lurie Children’s Hospital of Chicago, Chicago, IL, United States of America, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America

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• Patrick McGann,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  Affiliations Lifespan Comprehensive Sickle Cell Center, Providence, RI, United States of America, The Warren Alpert Medical School of Brown University, Providence, RI, United States of America

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• Savannah Winkler,

  Roles Investigation, Project administration, Writing – review & editing

  Affiliation Division of Hematology, Oncology, and Stem Cell Transplant, Lurie Children’s Hospital of Chicago, Chicago, IL, United States of America

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• Lisbel Gonzalez,

  Roles Investigation, Project administration, Writing – review & editing

  Affiliation Lifespan Comprehensive Sickle Cell Center, Providence, RI, United States of America

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• Susan Creary

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: susan.creary@nationwidechildrens.org

  Affiliations Center for Child Health Equity and Outcomes Research, The Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH, United States of America, Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, United States of America

  https://orcid.org/0000-0002-4730-8139

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