Cardiac manifestations of Fabry disease in G3Stg/GlaKO and GlaKO mouse models–Translation to Fabry disease patients

• Abirami Kugadas ,

  Contributed equally to this work with: Abirami Kugadas, Pietro Artoni

  Roles Formal analysis, Methodology, Validation, Writing – review & editing

  Affiliations Rare Diseases Drug Discovery Unit, Takeda Development Center Americas Inc., Cambridge, Massachusetts, United States of America, Oncology and Immunology Unit, WuXi AppTec, Natick, Massachusetts, United States of America

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• Pietro Artoni ,

  Contributed equally to this work with: Abirami Kugadas, Pietro Artoni

  Roles Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliation Statistical and Quantitative Sciences, Takeda Development Center Americas Inc., Cambridge, Massachusetts, United States of America

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• Wanida Ruangsiriluk,

  Roles Conceptualization, Investigation, Methodology, Validation, Writing – review & editing

  Affiliations Rare Diseases Drug Discovery Unit, Takeda Development Center Americas Inc., Cambridge, Massachusetts, United States of America, Crosswalk Therapeutics, Cambridge, Massachusetts, United States of America

  https://orcid.org/0009-0008-5168-7582

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• Meng Zhao,

  Roles Formal analysis, Investigation, Methodology, Software, Validation, Writing – review & editing

  Affiliation Statistical and Quantitative Sciences, Takeda Development Center Americas Inc., Cambridge, Massachusetts, United States of America

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• Natalia Boukharov,

  Roles Conceptualization, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliations Rare Diseases Drug Discovery Unit, Takeda Development Center Americas Inc., Cambridge, Massachusetts, United States of America, Crosswalk Therapeutics, Cambridge, Massachusetts, United States of America

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• Rizwana Islam,

  Roles Conceptualization, Investigation, Project administration, Supervision, Validation, Writing – review & editing

  Affiliations Rare Diseases Drug Discovery Unit, Takeda Development Center Americas Inc., Cambridge, Massachusetts, United States of America, Crosswalk Therapeutics, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0002-1613-6370

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• Dmitri Volfson ,

  Roles Conceptualization, Investigation, Methodology, Resources, Software, Supervision, Writing – review & editing

  * E-mail: kathydk2003@yahoo.com, kderakhchan@flagshippioneering.com (KD); dmitri.volfson@takeda.com (DV)

  Affiliation Statistical and Quantitative Sciences, Takeda Development Center Americas Inc., Cambridge, Massachusetts, United States of America

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• Katayoun Derakhchan

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: kathydk2003@yahoo.com, kderakhchan@flagshippioneering.com (KD); dmitri.volfson@takeda.com (DV)

  Affiliations Rare Diseases Drug Discovery Unit, Takeda Development Center Americas Inc., Cambridge, Massachusetts, United States of America, Pioneering Medicines at Flagship Pioneering, Cambridge, Massachusetts, United States of America

  https://orcid.org/0009-0004-3807-2701

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