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Trauma patients have reduced ex vivo flow-dependent platelet hemostatic capacity in a microfluidic model of vessel injury
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Kimberly A. Thomas ,
Contributed equally to this work with: Kimberly A. Thomas, Rassam M. G. Rassam
Roles Conceptualization, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing
Affiliation Vitalant Research Institute, Denver, Colorado, United States of America
⨯ - Rassam M. G. Rassam ,
- Ronit Kar,
- Devin M. Dishong,
- Katelin C. Rahn,
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Ricardo Fonseca,
Roles Data curation, Investigation, Methodology, Project administration, Supervision, Writing – review & editing
Affiliation Department of Surgery, Washington University in St. Louis, St. Louis, Missouri, United States of America
⨯ - Melissa Canas,
- Jose Aldana,
- Hussain Afzal,
- Kelly Bochicchio,
- Matthew D. Neal,
- Grant V. Bochicchio,
- Philip C. Spinella,
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Susan M. Shea
Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: smshea@pitt.edu
Affiliations Trauma and Transfusion Medicine Research Center (TTMRC), Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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https://orcid.org/0000-0001-8152-9974
Trauma patients have reduced ex vivo flow-dependent platelet hemostatic capacity in a microfluidic model of vessel injury
- Kimberly A. Thomas,
- Rassam M. G. Rassam,
- Ronit Kar,
- Devin M. Dishong,
- Katelin C. Rahn,
- Ricardo Fonseca,
- Melissa Canas,
- Jose Aldana,
- Hussain Afzal,
- Kelly Bochicchio
- Published: July 10, 2024
- https://doi.org/10.1371/journal.pone.0304231