Clinical safety and pharmacokinetics of a novel oral niclosamide formulation compared with marketed niclosamide chewing tablets in healthy volunteers: A three-part randomized, double-blind, placebo-controlled trial

• Niklas Walther,

  Roles Conceptualization, Investigation, Writing – original draft

  Affiliations Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany, Charité Research Organisation GmbH, Berlin, Germany

  https://orcid.org/0000-0002-2102-5835

  ⨯
• Robert Schultz-Heienbrok ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Writing – review & editing

  * E-mail: robert.schultz-heienbrok@charite-research.org

  Affiliation Charité Research Organisation GmbH, Berlin, Germany

  ⨯
• Heino Staß,

  Roles Data curation, Formal analysis, Methodology, Resources, Software, Validation, Visualization

  Affiliation Bayer AG, Research & Development, Pharmaceuticals, Wuppertal, Germany

  ⨯
• Victor M. Corman,

  Roles Conceptualization, Writing – review & editing

  Affiliations Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany, German Center for Infection Research, Braunschweig, Germany

  ⨯
• Nils C. Gassen,

  Roles Writing – review & editing

  Affiliations Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany

  ⨯
• Marcel A. Müller,

  Roles Conceptualization, Writing – review & editing

  Affiliations Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany, German Center for Infection Research, Braunschweig, Germany

  ⨯
• Christian Drosten,

  Roles Conceptualization, Writing – review & editing

  Affiliations Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany, German Center for Infection Research, Braunschweig, Germany

  ⨯
• Martin Witzenrath,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliations Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, German Center for Lung Research, Berlin, Germany

  ⨯
• Hweeling Lee,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation Charité Research Organisation GmbH, Berlin, Germany

  ⨯
• Maximilian G. Posch

  Roles Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing

  Current address: SCIRENT Clinical Research and Science GmbH, Berlin, Germany

  Affiliation Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany

  ⨯