Combined use of Panax notoginseng and leech provides new insights into renal fibrosis: Restoration of mitochondrial kinetic imbalance

Xin Chen; Jingwei Deng; Ling Zuo; Hongyu Luo; Munan Wang; Peng Deng; Kang Yang; Qian Yang; Xuekuan Huang

doi:10.1371/journal.pone.0303906

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Open Access

Peer-reviewed

Research Article

Combined use of Panax notoginseng and leech provides new insights into renal fibrosis: Restoration of mitochondrial kinetic imbalance

Xin Chen,

Roles Conceptualization, Formal analysis, Investigation, Software, Visualization, Writing – original draft

Affiliations College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing, China

https://orcid.org/0009-0007-8976-1453

⨯
Jingwei Deng,

Roles Investigation, Software, Supervision

Affiliations College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing, China
⨯
Ling Zuo,

Roles Supervision, Writing – review & editing

Affiliations College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing, China
⨯
Hongyu Luo,

Roles Writing – review & editing

Affiliations College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing, China
⨯
Munan Wang,

Roles Validation

Affiliations College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing, China
⨯
Peng Deng,

Roles Investigation, Software, Supervision

Affiliations College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing, China
⨯
Kang Yang,

Roles Investigation

Affiliations College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing, China
⨯
Qian Yang,

Roles Investigation

Affiliations College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, Chongqing, China
⨯
Xuekuan Huang

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision

* E-mail: xkhuang2002@163.com

Affiliation College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, China

https://orcid.org/0000-0002-9507-6678

⨯

Combined use of Panax notoginseng and leech provides new insights into renal fibrosis: Restoration of mitochondrial kinetic imbalance

Xin Chen,
Jingwei Deng,
Ling Zuo,
Hongyu Luo,
Munan Wang,
Peng Deng,
Kang Yang,
Qian Yang,
Xuekuan Huang

Published: May 29, 2024
https://doi.org/10.1371/journal.pone.0303906

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Mitochondria
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Fibrosis
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Leeches
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Renal system
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Oxidative stress
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Kidneys
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Antioxidants
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Renal analysis
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