Reversal of diabetes by an oral Salmonella-based vaccine in acute and progressive diabetes in NOD mice

Jacob Cobb; Jeffrey Rawson; Nelson Gonzalez; Chris Orr; Fouad Kandeel; Mohamed I. Husseiny

doi:10.1371/journal.pone.0303863

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Peer-reviewed

Research Article

Reversal of diabetes by an oral Salmonella-based vaccine in acute and progressive diabetes in NOD mice

Jacob Cobb,

Roles Data curation, Methodology, Writing – original draft

Affiliation Department of Translational Research & Cellular Therapeutics, Arthur Riggs Diabetes & Metabolism Research Institute, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America
⨯
Jeffrey Rawson,

Roles Data curation, Methodology

Affiliation Department of Translational Research & Cellular Therapeutics, Arthur Riggs Diabetes & Metabolism Research Institute, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America
⨯
Nelson Gonzalez,

Roles Data curation, Methodology

Affiliation Department of Translational Research & Cellular Therapeutics, Arthur Riggs Diabetes & Metabolism Research Institute, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America
⨯
Chris Orr,

Roles Formal analysis, Software, Writing – original draft

Affiliation Department of Translational Research & Cellular Therapeutics, Arthur Riggs Diabetes & Metabolism Research Institute, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America
⨯
Fouad Kandeel,

Roles Supervision, Writing – review & editing

Affiliation Department of Translational Research & Cellular Therapeutics, Arthur Riggs Diabetes & Metabolism Research Institute, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America
⨯
Mohamed I. Husseiny

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation, Writing – review & editing

* E-mail: melsayed@coh.org

Affiliation Department of Translational Research & Cellular Therapeutics, Arthur Riggs Diabetes & Metabolism Research Institute, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

https://orcid.org/0000-0002-3470-2858

⨯

Reversal of diabetes by an oral Salmonella-based vaccine in acute and progressive diabetes in NOD mice

Jacob Cobb,
Jeffrey Rawson,
Nelson Gonzalez,
Chris Orr,
Fouad Kandeel,
Mohamed I. Husseiny

Published: May 23, 2024
https://doi.org/10.1371/journal.pone.0303863

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Diabetes mellitus
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Blood sugar
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Vaccination and immunization
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Vaccines
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Progressive diseases
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Cytokines
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Insulin
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Vaccine development
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