An NGS-based assay for accurate detection and quantification of immune gene expression in mouse tumor models

Jia Xue; Xiaobo Chen; Xiaoyu An; Jingjing Wang; Mingfa Zang; Binchen Mao; Sheng Guo; Tao Yang; Rajendra Kumari; Qi-Xiang Li

doi:10.1371/journal.pone.0303171

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Open Access

Peer-reviewed

Research Article

An NGS-based assay for accurate detection and quantification of immune gene expression in mouse tumor models

Jia Xue ,

Contributed equally to this work with: Jia Xue, Xiaobo Chen

Roles Data curation, Formal analysis, Methodology, Writing – original draft

Affiliation Crown Bioscience, Inc., San Diego, California, United States of America

https://orcid.org/0000-0002-8048-752X

⨯
Xiaobo Chen ,

Contributed equally to this work with: Jia Xue, Xiaobo Chen

Roles Data curation, Formal analysis, Methodology, Writing – original draft

Affiliation Crown Bioscience, Inc., San Diego, California, United States of America
⨯
Xiaoyu An,

Roles Formal analysis, Methodology, Supervision

Affiliation Crown Bioscience, Inc., San Diego, California, United States of America
⨯
Jingjing Wang,

Roles Formal analysis, Methodology, Supervision

Affiliation Crown Bioscience, Inc., San Diego, California, United States of America
⨯
Mingfa Zang,

Roles Data curation, Formal analysis

Affiliation Crown Bioscience, Inc., San Diego, California, United States of America
⨯
Binchen Mao,

Roles Data curation, Formal analysis, Methodology, Validation

Affiliation Crown Bioscience, Inc., San Diego, California, United States of America
⨯
Sheng Guo,

Roles Methodology, Supervision, Writing – original draft, Writing – review & editing

Affiliation Crown Bioscience, Inc., San Diego, California, United States of America
⨯
Tao Yang,

Roles Data curation, Methodology

Affiliation Crown Bioscience, Inc., San Diego, California, United States of America
⨯
Rajendra Kumari,

Roles Formal analysis, Writing – original draft, Writing – review & editing

Affiliation Crown Bioscience, Inc., San Diego, California, United States of America
⨯
Qi-Xiang Li

Roles Conceptualization, Writing – original draft, Writing – review & editing

* E-mail: hqxl@yahoo.com

Affiliation Crown Bioscience, Inc., San Diego, California, United States of America

https://orcid.org/0000-0002-4673-1234

⨯

An NGS-based assay for accurate detection and quantification of immune gene expression in mouse tumor models

Jia Xue,
Xiaobo Chen,
Xiaoyu An,
Jingjing Wang,
Mingfa Zang,
Binchen Mao,
Sheng Guo,
Tao Yang,
Rajendra Kumari,
Qi-Xiang Li

Published: May 20, 2024
https://doi.org/10.1371/journal.pone.0303171

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Cancers and neoplasms
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RNA sequencing
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Gene expression
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Immune cells
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